Despite significant advancements made in the treatment of cancer during the past several
decades, it remains one of the leading causes of death worldwide killing approximately 9.6 …

Simple Summary The chorioallantoic membrane (CAM) model is an alternative in vivo test
system for the study of hallmarks of cancer such as angiogenesis, tumor growth, immune …

Abstract Background Cancer stem cells (CSCs) are strongly associated with high
tumourigenicity, chemotherapy or radiotherapy resistance, and metastasis and recurrence …

In the last decade, the chicken chorioallantoic membrane (CAM) assay has been re-
discovered in cancer research to study the molecular mechanisms of anti-cancer drug …

Simple Summary Colorectal cancer (CRC) is an emerging public health problem and the
second leading cause of death worldwide, with a significant socioeconomic impact in …

Simple Summary Radiotherapy is a standard of care therapy that kills cancer cells but has
limited efficacy in targeting the resistant cancer stem cells (CSCs). The use of …

Cancer is a worldwide disease that causes millions of cases of mortality and morbidity. The
major problem associated with the cancer is its resistance to conventional therapy and a …

The long-term success of standard anticancer monotherapeutic strategies has been
hampered by intolerable side effects, resistance to treatment and cancer relapse. These …

The high recurrence rates of colorectal cancer have been associated with a small population
of cancer stem cells (CSCs) that are resistant to the standard chemotherapeutic drug, 5 …

Abstract In 2010, the European Parliament and the European Union adopted a directive on
the protection of animals used for scientific purposes. The directive aims to protect animals …