Bone marrow mesenchymal stem/stromal cells (BMSCs), which are known as multipotent
cells, are widely used in the treatment of various diseases via their self-renewable …

The interest in bone marrow adiposity (BMA) has increased over the last decade due to its
association with, and potential role, in a range of diseases (osteoporosis, diabetes …

Decline in hematopoietic stem cell (HSC) function with age underlies limited health span of
our blood and immune systems. In order to preserve health into older age, it is necessary to …

Background Exosomes, widely recognized natural nanovesicles, represent one of the
recently discovered modes of intercellular communication due to their ability to transmit …

Functional delivery of mRNA to tissues in the body is key to implementing fundamentally
new and potentially transformative strategies for vaccination, protein replacement therapy …

Lipopolysaccharide (LPS)-preconditioned mesenchymal stem cells (MSCs) possessed
strong immunomodulatory and anti-inflammatory functions by secreting exosomes as major …

Functional reconstruction of craniomaxillofacial defects is challenging, especially for the
patients who suffer from traumatic injury, cranioplasty, and oncologic surgery. Three …

Background Periodontitis is caused by the imbalance of anti‐bacteria immune response and
excessive inflammation whereas macrophages play an important role in inflammation. Thus …

Rationale: Angiogenesis and osteogenesis are highly coupled processes which are
indispensable to bone repair. However, the underlying mechanism (s) remain elusive. To …

ABSTRACT Fibroblast growth factor 9 (Fgf9) is a well‐known factor that regulates bone
development; however, its function in bone homeostasis is still unknown. Previously, we …