MicroRNAs (miRNAs) are naturally occurring, small non-coding RNAs that mediate
posttranscriptional regulation. Based on the level of sequence complementarity, miRNAs …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the main cause
of dementia among the elderly worldwide. Despite intense efforts to develop drugs for …

The human genome encodes a vast repertoire of protein non-coding RNAs (ncRNA), some
specific to the brain. MicroRNAs, which interfere with the translation of target mRNAs, are of …

The identification of mechanisms associated with Alzheimer's disease (AD) development in
mild cognitive impairment (MCI) would be of great usefulness to clarify AD pathogenesis and …

Alzheimer's disease (AD) is a progressive mental illness characterized by memory loss and
multiple cognitive impairments. In the last several decades, significant progress has been …

Histone deacetylase 2 (HDAC2) plays a major role in the epigenetic regulation of gene
expression. Previous studies have shown that HDAC2 expression is strongly increased in …

Epigenetic modifications are emerging as major players in the pathogenesis of
neurodegenerative disorders and susceptibility to acute brain injury. DNA and histone …

As the most common neurodegenerative disease, Alzheimer's disease (AD) is characterized
by memory, perception, and behavioral damage, which may ultimately lead to emotional …

Alzheimer's disease (AD), with main clinical features of progressive impairment in cognitive
and behavioral functions, is the most common degenerative disease of the central nervous …

Non-coding RNAs (ncRNAs), including miRNAs, lncRNAs, circRNAs, and piRNAs, do not
encode proteins. Nonetheless, they have critical roles in a variety of cellular activities—such …