Simple Summary Growth factors are hormone-like molecules able to promote division and
migration of normal cells, but cancer captured the underlying mechanisms to unleash tumor …

Prostate cancer (PCa) is one of the most commonly diagnosed malignancies and among the
leading causes of cancer-related death worldwide. It is a highly heterogeneous disease …

Abstract Background Gene Expression database of Normal and Tumor tissues 2 (GENT2) is
an updated version of GENT, which has provided a user-friendly search platform for gene …

The epidermal growth factor receptor (EGFR) is one of most potent oncogenes that are
commonly altered in cancers. As a receptor tyrosine kinase, EGFR's kinase activity has been …

Ability to form cellular aggregations such as tumorspheres and spheroids have been used
as a morphological marker of malignant cancer cells and in particular cancer stem cells …

Simple Summary Prostate cancer can develop under hormone treatment and chemotherapy
from a castration-sensitive towards a castration-resistant into a drug resistant-tumor. The …

Prostate cancer (PCa) is a leading cause of death for men worldwide. Most PCa patients die
from metastasis and bone is the most common metastatic site. Three dimensional (3D) …

Prostate cancer (PCa) is heterogeneous, harboring phenotypically diverse cancer cell types.
PCa cell heterogeneity is caused by genomic instability that leads to the clonal competition …

There is growing demand for novel biomarkers that detect early stage disease as well as
monitor clinical management and therapeutic strategies. Exosome analysis could provide …

Research in the last decade has clearly revealed a critical role of prostate cancer stem cells
(PCSCs) in prostate cancer (PC). Prostate stem cells (PSCs) reside in both basal and …