Update on hepatitis E virology: Implications for clinical practice

Y Debing, D Moradpour, J Neyts, J Gouttenoire - Journal of hepatology, 2016 - Elsevier
Hepatitis E virus (HEV) is a positive-strand RNA virus transmitted by the fecal-oral route. The
7.2 kb genome encodes three open reading frames (ORF) which are translated into (i) the …

[HTML][HTML] Sweeten PAMPs: role of sugar complexed PAMPs in innate immunity and vaccine biology

RS Mahla, MC Reddy, DVR Prasad… - Frontiers in …, 2013 - frontiersin.org
Innate sensors play a critical role in the early innate immune responses to invading
pathogens through sensing of diverse biochemical signatures also known as pathogen …

[HTML][HTML] Clinical manifestations, pathogenesis and treatment of hepatitis E virus infections

S Lhomme, O Marion, F Abravanel, J Izopet… - Journal of clinical …, 2020 - mdpi.com
Hepatitis E virus (HEV) is the most common cause of acute viral hepatitis throughout the
world. Most infections are acute but they can become chronic in immunocompromised …

Modulation of the innate immune response by targeting toll-like receptors: a perspective on their agonists and antagonists

S Federico, L Pozzetti, A Papa, G Carullo… - Journal of Medicinal …, 2020 - ACS Publications
Toll-like receptors (TLRs) are a class of proteins that recognize pathogen-associated
molecular patterns (PAMPs) and damaged-associated molecular patterns (DAMPs), and …

[HTML][HTML] Hepatitis E pathogenesis

S Lhomme, O Marion, F Abravanel, S Chapuy-Regaud… - Viruses, 2016 - mdpi.com
Although most hepatitis E virus (HEV) infections are asymptomatic, some can be severe,
causing fulminant hepatitis and extra-hepatic manifestations, including neurological and …

[HTML][HTML] Current knowledge on hepatitis E

MT Pérez-Gracia, M García, B Suay… - Journal of clinical and …, 2015 - ncbi.nlm.nih.gov
Although only a single serotype of hepatitis E virus (HEV), the causative agent of hepatitis E,
has been identified, there is great genetic variation among the different HEV isolates …

Hepeviridae: an expanding family of vertebrate viruses

R Johne, P Dremsek, J Reetz, G Heckel, M Hess… - Infection, Genetics and …, 2014 - Elsevier
The hepatitis E virus (HEV) was first identified in 1990, although hepatitis E-like diseases in
humans have been recorded for a long time dating back to the 18th century. The HEV …

Hepatitis E virus replication in human intestinal cells

O Marion, S Lhomme, M Nayrac, M Dubois, M Pucelle… - Gut, 2020 - gut.bmj.com
Objective Hepatitis E virus (HEV), one of the most common agent of acute hepatitis
worldwide, is mainly transmitted enterically, via contaminated water for HEV genotypes 1 …

[HTML][HTML] A review on plant extract mediated green synthesis of zinc oxide nanoparticles and their biomedical applications

MY Al-darwesh, SS Ibrahim, MA Mohammed - Results in Chemistry, 2024 - Elsevier
Abstract Zinc oxide nanoparticles (ZnO NPs) exhibit distinctive characteristics, making them
highly sought-after in many sectors. Nevertheless, conventional techniques for producing …

[HTML][HTML] Hepatitis E virus persists in the presence of a type III interferon response

X Yin, X Li, C Ambardekar, Z Hu, S Lhomme… - PLoS …, 2017 - journals.plos.org
The RIG-I-like RNA helicase (RLR)-mediated interferon (IFN) response plays a pivotal role
in the hepatic antiviral immunity. The hepatitis A virus (HAV) and the hepatitis C virus (HCV) …