Highlights•Metabolomics has become a widely applied tool in drug development.•
Metabolomics plays a key role for the identification of physiological response markers.• …

Nonresolving inflammation contributes to many diseases, including COVID-19 in its fatal and
long forms. Our understanding of inflammation is rapidly evolving. Like the immune system …

Monocyte-derived macrophages (MDM) drive the inflammatory response to severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and they are a major source of …

Female breast cancer emerged as the leading cancer type in terms of incidence globally in
2020. Although mortality due to breast cancer has improved during the past three decades …

Cell-selective proteomics is a powerful emerging concept to study heterocellular processes
in tissues. However, its high potential to identify non-cell-autonomous disease mechanisms …

Sepsis is a systemic inflammatory disease caused by an infection that can lead to multiple
organ failure. Sepsis alters energy metabolism, leading to metabolic reprogramming of …

Neurons migrate from their birthplaces to the destinations, and extending axons navigate to
their synaptic targets by sensing various extracellular cues in spatiotemporally controlled …

Targeting specific organs and cell types using nanotechnology and sophisticated delivery
methods has been at the forefront of applicative biomedical sciences lately. Macrophages …

Genetic polymorphisms are associated with the development of nonalcoholic fatty liver
disease (NAFLD). Semaphorin7a (Sema7a) deficiency in mouse peritoneal macrophages …

Human-adipose-derived mesenchymal stem cells (hADMSCs) are adult stem cells and are
relatively easy to access compared to other sources of mesenchymal stem cells (MSCs) …