The prefrontal cortex, pathological anxiety, and anxiety disorders

MM Kenwood, NH Kalin, H Barbas - Neuropsychopharmacology, 2022 - nature.com
Anxiety is experienced in response to threats that are distal or uncertain, involving changes
in one's subjective state, autonomic responses, and behavior. Defensive and physiologic …

Contextual inference in learning and memory

JB Heald, M Lengyel, DM Wolpert - Trends in cognitive sciences, 2023 - cell.com
Context is widely regarded as a major determinant of learning and memory across
numerous domains, including classical and instrumental conditioning, episodic memory …

Reinforcement learning in patients with mood and anxiety disorders vs control individuals: A systematic review and meta-analysis

AC Pike, OJ Robinson - JAMA psychiatry, 2022 - jamanetwork.com
Importance Computational psychiatry studies have investigated how reinforcement learning
may be different in individuals with mood and anxiety disorders compared with control …

[HTML][HTML] Don't fear 'fear conditioning': Methodological considerations for the design and analysis of studies on human fear acquisition, extinction, and return of fear

TB Lonsdorf, MM Menz, M Andreatta… - Neuroscience & …, 2017 - Elsevier
The so-called 'replicability crisis' has sparked methodological discussions in many areas of
science in general, and in psychology in particular. This has led to recent endeavours to …

Adults with autism overestimate the volatility of the sensory environment

RP Lawson, C Mathys, G Rees - Nature neuroscience, 2017 - nature.com
Insistence on sameness and intolerance of change are among the diagnostic criteria for
autism spectrum disorder (ASD), but little research has addressed how people with ASD …

How emotions are made: The secret life of the brain

LF Barrett - Pan Macmillan, 2017 - books.google.com
'How Emotions Are Made did what all great books do. It took a subject I thought I understood
and turned my understanding upside down'–Malcolm Gladwell, author of The Tipping Point …

The role of the locus coeruleus in the generation of pathological anxiety

LS Morris, JG McCall, DS Charney… - Brain and …, 2020 - journals.sagepub.com
This review aims to synthesise a large pre-clinical and clinical literature related to a
hypothesised role of the locus coeruleus norepinephrine system in responses to acute and …

The nature and neurobiology of fear and anxiety: State of the science and opportunities for accelerating discovery

SE Grogans, E Bliss-Moreau, KA Buss, LA Clark… - Neuroscience & …, 2023 - Elsevier
Fear and anxiety play a central role in mammalian life, and there is considerable interest in
clarifying their nature, identifying their biological underpinnings, and determining their …

The locus coeruleus-norepinephrine system in stress and arousal: unraveling historical, current, and future perspectives

JA Ross, EJ Van Bockstaele - Frontiers in psychiatry, 2021 - frontiersin.org
Arousal may be understood on a spectrum, with excessive sleepiness, cognitive dysfunction,
and inattention on one side, a wakeful state in the middle, and hypervigilance, panic, and …

Neuromodulatory correlates of pupil dilation

RS Larsen, J Waters - Frontiers in neural circuits, 2018 - frontiersin.org
Pupillometry has long been used as a measure of brain state. Changes in pupil diameter are
thought to coincide with the activity of neuromodulators, including noradrenaline and …