[HTML][HTML] Revisiting host-pathogen interactions in cystic fibrosis lungs in the era of CFTR modulators
CMP Ribeiro, MG Higgs, MS Muhlebach… - International Journal of …, 2023 - mdpi.com
Cystic fibrosis transmembrane conductance regulator (CFTR) modulators, a new series of
therapeutics that correct and potentiate some classes of mutations of the CFTR, have …
therapeutics that correct and potentiate some classes of mutations of the CFTR, have …
Functional Materials to Overcome Bacterial Barriers and Models to Advance Their Development
A Bali, MAM Kamal, G Mulla, B Loretz… - Advanced Functional …, 2023 - Wiley Online Library
With the emerging problem of antimicrobial resistance, the world is facing a slow but
dangerous pandemic. While the discovery of novel antibiotics is reaching a nearly …
dangerous pandemic. While the discovery of novel antibiotics is reaching a nearly …
Pseudomonas aeruginosa in chronic lung disease: untangling the dysregulated host immune response
R Nickerson, CS Thornton, B Johnston… - Frontiers in …, 2024 - frontiersin.org
Pseudomonas aeruginosa is a highly adaptable opportunistic pathogen capable of
exploiting barriers and immune defects to cause chronic lung infections in conditions such …
exploiting barriers and immune defects to cause chronic lung infections in conditions such …
The power of weak, transient interactions across biology: A paradigm of emergent behavior
A growing list of diverse biological systems and their equally diverse functionalities provides
realizations of a paradigm of emergent behavior. In each of these biological systems …
realizations of a paradigm of emergent behavior. In each of these biological systems …
[HTML][HTML] Altering the viscoelastic properties of mucus-grown Pseudomonas aeruginosa biofilms affects antibiotic susceptibility
KR Rouillard, MR Markovetz, WJ Kissner, WL Boone… - Biofilm, 2023 - Elsevier
The viscoelastic properties of biofilms are correlated with their susceptibility to mechanical
and chemical stress, and the airway environment in muco-obstructive pulmonary diseases …
and chemical stress, and the airway environment in muco-obstructive pulmonary diseases …
[HTML][HTML] Ceragenin-mediated disruption of Pseudomonas aeruginosa biofilms
U Wnorowska, D Łysik, E Piktel, M Zakrzewska, S Okła… - Plos one, 2024 - journals.plos.org
Background Microbial biofilms, as a hallmark of cystic fibrosis (CF) lung disease and other
chronic infections, remain a desirable target for antimicrobial therapy. These biopolymer …
chronic infections, remain a desirable target for antimicrobial therapy. These biopolymer …
Extracellular DNA enhances biofilm integrity and mechanical properties of mucoid Pseudomonas aeruginosa
Pseudomonas aeruginosa is one of the most common biofilm-forming pathogens
responsible for lung infections of individuals with cystic fibrosis (CF). P. aeruginosa becomes …
responsible for lung infections of individuals with cystic fibrosis (CF). P. aeruginosa becomes …
[HTML][HTML] Evaluation of black soldier fly larvae meal as a functional feed ingredient in Atlantic salmon (Salmo salar) under farm-like conditions
G Radhakrishnan, NS Liland, MW Koch… - Frontiers in …, 2023 - frontiersin.org
Atlantic salmon (Salmo salar) were fed diets containing black soldier fly larvae (BSFL) meal
at two inclusion levels for 13 months in open sea-cages. BSFL meal replaced plant-based …
at two inclusion levels for 13 months in open sea-cages. BSFL meal replaced plant-based …
Comprehensive characterization of the viscoelastic properties of Bovine Submaxillary Mucin (BSM) hydrogels and the effect of additives
H Rulff, RF Schmidt, LF Wei, K Fentker… - …, 2024 - ACS Publications
This study presents a comprehensive characterization of the viscoelastic and structural
properties of bovine submaxillary mucin (BSM), which is widely used as a commercial …
properties of bovine submaxillary mucin (BSM), which is widely used as a commercial …
Mucus polymer concentration and in vivo adaptation converge to define the antibiotic response of Pseudomonas aeruginosa during chronic lung infection
The airway milieu of individuals with muco-obstructive airway diseases (MADs) is defined by
the accumulation of dehydrated mucus due to hyperabsorption of airway surface liquid and …
the accumulation of dehydrated mucus due to hyperabsorption of airway surface liquid and …