Guidelines for experimental models of myocardial ischemia and infarction

ML Lindsey, R Bolli, JM Canty Jr… - American Journal …, 2018 - journals.physiology.org
Myocardial infarction is a prevalent major cardiovascular event that arises from myocardial
ischemia with or without reperfusion, and basic and translational research is needed to …

Stem cell therapy in heart diseases–cell types, mechanisms and improvement strategies

P Müller, H Lemcke, R David - Cellular Physiology and Biochemistry, 2018 - karger.com
A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

Guidelines for in vivo mouse models of myocardial infarction

ML Lindsey, KR Brunt, JA Kirk… - American Journal …, 2021 - journals.physiology.org
Despite significant improvements in reperfusion strategies, acute coronary syndromes all too
often culminate in a myocardial infarction (MI). The consequent MI can, in turn, lead to …

Bcl-2 engineered MSCs inhibited apoptosis and improved heart function

W Li, N Ma, LL Ong, C Nesselmann, C Klopsch… - Stem …, 2007 - academic.oup.com
Engraftment of mesenchymal stem cells (MSCs) derived from adult bone marrow has been
proposed as a potential therapeutic approach for postinfarction left ventricular dysfunction …

[HTML][HTML] Intramyocardial delivery of CD133+ bone marrow cells and coronary artery bypass grafting for chronic ischemic heart disease: safety and efficacy studies

C Stamm, HD Kleine, YH Choi, S Dunkelmann… - The Journal of thoracic …, 2007 - Elsevier
OBJECTIVES: Cell therapy may offer novel therapeutic options for chronic ischemic heart
disease. In a clinical trial, we first assessed the feasibility and safety of intramyocardial …

Uterine stem cells: from basic research to advanced cell therapies

X Santamaria, A Mas, I Cervelló… - Human Reproduction …, 2018 - academic.oup.com
BACKGROUND Stem cell research in the endometrium and myometrium from animal
models and humans has led to the identification of endometrial/myometrial stem cells and …

Mesenchymal stromal cells from umbilical cord blood

K Bieback, H Kluter - Current stem cell research & therapy, 2007 - ingentaconnect.com
Mesenchymal Stromal Cells (MSC) are key candidates for cellular therapies. Although most
therapeutic applications have focused on adult bone marrow derived MSC, increasing …

Cell origin of human mesenchymal stem cells determines a different healing performance in cardiac regeneration

R Gaebel, D Furlani, H Sorg, B Polchow, J Frank… - Plos one, 2011 - journals.plos.org
The possible different therapeutic efficacy of human mesenchymal stem cells (hMSC)
derived from umbilical cord blood (CB), adipose tissue (AT) or bone marrow (BM) for the …

Embryonic stem cell–derived endothelial cells engraft into the ischemic hindlimb and restore perfusion

NF Huang, H Niiyama, C Peter, A De… - … , and vascular biology, 2010 - Am Heart Assoc
Objective—We examined the effect of delivery modality on the survival, localization, and
functional effects of exogenously administered embryonic stem cells (ESCs) or endothelial …

Autologous CD133+ bone marrow cells and bypass grafting for regeneration of ischaemic myocardium: the Cardio133 trial

BA Nasseri, W Ebell, M Dandel, M Kukucka… - European heart …, 2014 - academic.oup.com
Aims Intra-myocardial transplantation of CD133+ bone marrow stem cells (BMC) yielded
promising results in clinical pilot trials. We now performed the double-blinded, randomized …