Prion diseases are transmissible spongiform encephalopathies (TSEs), attributed to
conformational conversion of the cellular prion protein (PrPC) into an abnormal conformer …

The etiologies of neurodegenerative diseases may be diverse; however, a common
pathological denominator is the formation of aberrant protein conformers and the occurrence …

Misfolded alpha-synuclein (αSyn) is a major constituent of Lewy bodies and Lewy neurites,
which are pathological hallmarks of Parkinson's disease (PD). The contribution of αSyn to …

The prion (infectious protein) concept has evolved with the discovery of new self-
propagating protein states in organisms as diverse as mammals and fungi. The infectious …

Kinetics of high temperature oxygen reduction reaction (ORR) on La 2 NiO 4+ δ (LNO)
nanostructures are investigated by means of electrochemical impedance spectroscopy, with …

A peptide derived from the N-terminus of the unprocessed bovine prion protein (bPrPp),
incorporating the hydrophobic signal sequence (residues 1–24) and a basic domain …

The conversion of prion protein (PrP) to the pathogenic PrPSc conformation is central to
prion disease. Previous studies revealed that PrP interacts with lipids and the interaction …

Various fatal neurodegenerative disorders are caused by altered metabolism of the prion
protein (PrP). These diseases are typically transmissible by an unusual 'protein …

The cellular prion protein (PrP C), which is present ubiquitously in all mammalian neurons,
is normally found to be linked to the cell membrane through a glycosylphosphatidylinositol …

Converting normal prion protein (PrPC) to the pathogenic PrPSc isoform is central to prion
disease. We previously showed that, in the presence of lipids, recombinant mouse PrP …