Anion transport and supramolecular medicinal chemistry

PA Gale, JT Davis, R Quesada - Chemical Society Reviews, 2017 - pubs.rsc.org
New approaches to the transmembrane transport of anions are discussed in this review.
Advances in the design of small molecule anion carriers are reviewed in addition to …

Stimulus-controlled anion binding and transport by synthetic receptors

J de Jong, JE Bos, SJ Wezenberg - Chemical Reviews, 2023 - ACS Publications
Anionic species are omnipresent and involved in many important biological processes. A
large number of artificial anion receptors has therefore been developed. Some of these are …

Photomodulation of transmembrane transport and potential by stiff-stilbene based bis (thio) ureas

SJ Wezenberg, LJ Chen, JE Bos… - Journal of the …, 2021 - ACS Publications
Membrane transport proteins fulfill important regulatory functions in biology with a common
trait being their ability to respond to stimuli in the environment. Various small-molecule …

Self‐assembled artificial ion‐channels toward natural selection of functions

S Zheng, L Huang, Z Sun… - Angewandte Chemie …, 2021 - Wiley Online Library
Owing to their significant physiological functions, especially as selective relays for
translocation of physiological relevant species through cellular membranes, natural ion …

A synthetic ion transporter that disrupts autophagy and induces apoptosis by perturbing cellular chloride concentrations

N Busschaert, SH Park, KH Baek, YP Choi, J Park… - Nature …, 2017 - nature.com
Perturbations in cellular chloride concentrations can affect cellular pH and autophagy and
lead to the onset of apoptosis. With this in mind, synthetic ion transporters have been used to …

Molecular Machines For The Control Of Transmembrane Transport

TG Johnson, MJ Langton - Journal of the American Chemical …, 2023 - ACS Publications
Nature embeds some of its molecular machinery, including ion pumps, within lipid bilayer
membranes. This has inspired chemists to attempt to develop synthetic analogues to exploit …

Anion binding in solution: beyond the electrostatic regime

Y Liu, A Sengupta, K Raghavachari, AH Flood - Chem, 2017 - cell.com
A fundamental understanding of anion binding by receptors is essential for managing salts
during energy, water, and food production. However, the limited understanding of solvent …

Anion receptor chemistry: Highlights from 2016

PA Gale, ENW Howe, X Wu, MJ Spooner - Coordination Chemistry Reviews, 2018 - Elsevier
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Photoswitchable Bis (amidopyrroles): Modulating Anion Transport Activity Independent of Binding Affinity

D Villarón, JE Bos, F Kohl, S Mommer… - The Journal of …, 2023 - ACS Publications
Toward photocontrol of anion transport across the bilayer membrane, stiff-stilbene, which
has dimethyl substituents in the five-membered rings, is functionalized with amidopyrrole …

Photocontrolled activation of doubly o-nitrobenzyl-protected small molecule benzimidazoles leads to cancer cell death

M Ahmad, NJ Roy, A Singh, D Mondal, A Mondal… - Chemical …, 2023 - pubs.rsc.org
Artificial biomimetic chloride anionophores have shown promising applications as
anticancer scaffolds. Importantly, stimuli-responsive chloride transporters that can be …