Anion transport and supramolecular medicinal chemistry
New approaches to the transmembrane transport of anions are discussed in this review.
Advances in the design of small molecule anion carriers are reviewed in addition to …
Advances in the design of small molecule anion carriers are reviewed in addition to …
Stimulus-controlled anion binding and transport by synthetic receptors
J de Jong, JE Bos, SJ Wezenberg - Chemical Reviews, 2023 - ACS Publications
Anionic species are omnipresent and involved in many important biological processes. A
large number of artificial anion receptors has therefore been developed. Some of these are …
large number of artificial anion receptors has therefore been developed. Some of these are …
Photomodulation of transmembrane transport and potential by stiff-stilbene based bis (thio) ureas
SJ Wezenberg, LJ Chen, JE Bos… - Journal of the …, 2021 - ACS Publications
Membrane transport proteins fulfill important regulatory functions in biology with a common
trait being their ability to respond to stimuli in the environment. Various small-molecule …
trait being their ability to respond to stimuli in the environment. Various small-molecule …
Self‐assembled artificial ion‐channels toward natural selection of functions
Owing to their significant physiological functions, especially as selective relays for
translocation of physiological relevant species through cellular membranes, natural ion …
translocation of physiological relevant species through cellular membranes, natural ion …
A synthetic ion transporter that disrupts autophagy and induces apoptosis by perturbing cellular chloride concentrations
N Busschaert, SH Park, KH Baek, YP Choi, J Park… - Nature …, 2017 - nature.com
Perturbations in cellular chloride concentrations can affect cellular pH and autophagy and
lead to the onset of apoptosis. With this in mind, synthetic ion transporters have been used to …
lead to the onset of apoptosis. With this in mind, synthetic ion transporters have been used to …
Molecular Machines For The Control Of Transmembrane Transport
TG Johnson, MJ Langton - Journal of the American Chemical …, 2023 - ACS Publications
Nature embeds some of its molecular machinery, including ion pumps, within lipid bilayer
membranes. This has inspired chemists to attempt to develop synthetic analogues to exploit …
membranes. This has inspired chemists to attempt to develop synthetic analogues to exploit …
Anion binding in solution: beyond the electrostatic regime
Y Liu, A Sengupta, K Raghavachari, AH Flood - Chem, 2017 - cell.com
A fundamental understanding of anion binding by receptors is essential for managing salts
during energy, water, and food production. However, the limited understanding of solvent …
during energy, water, and food production. However, the limited understanding of solvent …
Anion receptor chemistry: Highlights from 2016
Anion receptor chemistry: Highlights from 2016 - ScienceDirect Skip to main contentSkip to
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Photoswitchable Bis (amidopyrroles): Modulating Anion Transport Activity Independent of Binding Affinity
D Villarón, JE Bos, F Kohl, S Mommer… - The Journal of …, 2023 - ACS Publications
Toward photocontrol of anion transport across the bilayer membrane, stiff-stilbene, which
has dimethyl substituents in the five-membered rings, is functionalized with amidopyrrole …
has dimethyl substituents in the five-membered rings, is functionalized with amidopyrrole …
Photocontrolled activation of doubly o-nitrobenzyl-protected small molecule benzimidazoles leads to cancer cell death
Artificial biomimetic chloride anionophores have shown promising applications as
anticancer scaffolds. Importantly, stimuli-responsive chloride transporters that can be …
anticancer scaffolds. Importantly, stimuli-responsive chloride transporters that can be …