Nutritional implications of ginger: Chemistry, biological activities and signaling pathways

R Kiyama - The Journal of nutritional biochemistry, 2020 - Elsevier
Abstract Ginger (Zingiber officinale Roscoe) has been used as a food, spice, supplement
and flavoring agent and in traditional medicines due to its beneficial characteristics such as …

[HTML][HTML] Therapeutic potential of ginger against COVID-19: Is there enough evidence?

A Jafarzadeh, S Jafarzadeh, M Nemati - Journal of Traditional Chinese …, 2021 - Elsevier
In addition to the respiratory system, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) strikes other systems, including the digestive, circulatory, urogenital, and …

Zingerone reduces sodium arsenite-induced nephrotoxicity by regulating oxidative stress, inflammation, apoptosis and histopathological changes

N Akaras, C Gur, S Kucukler, FM Kandemir - Chemico-biological …, 2023 - Elsevier
Arsenic is widely available in the environment and arsenic toxicity is a public health problem
of serious concern worldwide. Zingerone is a promising phytochemical with various …

[HTML][HTML] Hesperidin and hesperetin against heavy metal toxicity: Insight on the molecular mechanism of mitigation

AC Famurewa, K Renu, MA Eladl… - Biomedicine & …, 2022 - Elsevier
Toxic heavy metals (THMs) are non-essential hazardous environmental pollutants with
intractable health challenges in humans and animals. Exposure to lead (Pb), cadmium (Cd) …

Protective effects of chrysin against oxidative stress and inflammation induced by lead acetate in rat kidneys: a biochemical and histopathological approach

S Kucukler, F Benzer, S Yildirim, C Gur… - … Trace Element Research, 2021 - Springer
In this study, the protective effects of chrysin (CR) on lead acetate (PbAc)-induced renal
toxicity in Sprague-Dawley rats were investigated with biochemical, histopathological, and …

Evaluation of protective effects of quercetin against cypermethrin‐induced lung toxicity in rats via oxidative stress, inflammation, apoptosis, autophagy, and …

M Ileriturk, O Kandemir… - Environmental …, 2022 - Wiley Online Library
Cypermethrin (CYP), a type II synthetic pyrethroid, is the most widely used insecticide
worldwide. Inhalation of it may cause side effects. This study is aimed to examine potential …

Rutin ameliorates mercuric chloride-induced hepatotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis

C Caglayan, FM Kandemir, E Darendelioğlu… - Journal of Trace …, 2019 - Elsevier
Objective Mercury is a global environmental pollutant and is responsible for several organ
pathophysiology including oxidative stress-induced liver disorders. Therefore, the present …

Protective effect of chrysin on cyclophosphamide-induced hepatotoxicity and nephrotoxicity via the inhibition of oxidative stress, inflammation, and apoptosis

Y Temel, S Kucukler, S Yıldırım, C Caglayan… - Naunyn-Schmiedeberg's …, 2020 - Springer
Cyclophosphamide (CYP) is a chemotherapeutic agent used in the treatment of autoimmune
disorders and malignant diseases. However, its usage is restricted due to its severe side …

Quercetin provides protection against the peripheral nerve damage caused by vincristine in rats by suppressing caspase 3, NF-κB, ATF-6 pathways and activating …

A Yardim, FM Kandemir, S Ozdemir, S Kucukler… - Neurotoxicology, 2020 - Elsevier
In the present study, the protective effects of quercetin on peripheral neurotoxicity caused by
vincristine, which is used effectively in the treatment of various types of cancers, were …

Neuroprotective effect of rutin against colistin-induced oxidative stress, inflammation and apoptosis in rat brain associated with the CREB/BDNF expressions

H Çelik, FM Kandemir, C Caglayan, S Özdemir… - Molecular biology …, 2020 - Springer
The purpose of the current study was to examine the neuroprotective effect of rutin against
colistin-induced neurotoxicity in rats. Thirty-five male Sprague Dawley rats were randomly …