The use of alternative strategies for enhanced nanoparticle delivery to solid tumors
M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …
decade. Classically, scientists have tried to improve NM delivery by employing passive or …
MicroRNA delivery through nanoparticles
MicroRNAs (miRNAs) are attracting a growing interest in the scientific community due to
their central role in the etiology of major diseases. On the other hand, nanoparticle carriers …
their central role in the etiology of major diseases. On the other hand, nanoparticle carriers …
Form follows function: nanoparticle shape and its implications for nanomedicine
This review is a comprehensive description of the past decade of research into
understanding how the geometry and size of nanoparticles affect their interaction with …
understanding how the geometry and size of nanoparticles affect their interaction with …
[HTML][HTML] Alliance with EPR effect: combined strategies to improve the EPR effect in the tumor microenvironment
The use of nanomedicine for cancer treatment takes advantage of its preferential
accumulation in tumors owing to the enhanced permeability and retention (EPR) effect. The …
accumulation in tumors owing to the enhanced permeability and retention (EPR) effect. The …
[HTML][HTML] Nanocarrier-based drug combination therapy for glioblastoma
M Zhao, D van Straten, MLD Broekman, V Préat… - Theranostics, 2020 - ncbi.nlm.nih.gov
The current achievements in treating glioblastoma (GBM) patients are not sufficient because
many challenges exist, such as tumor heterogeneity, the blood brain barrier, glioma stem …
many challenges exist, such as tumor heterogeneity, the blood brain barrier, glioma stem …
An overview of carboxymethyl derivatives of chitosan: Their use as biomaterials and drug delivery systems
B Fonseca-Santos, M Chorilli - Materials Science and Engineering: C, 2017 - Elsevier
Chitin is one of the most abundant natural polymers in the world and is used for the
production of chitosan by deacetylation. Chitosan is nontoxic and biodegradable and …
production of chitosan by deacetylation. Chitosan is nontoxic and biodegradable and …
Targeting tumor-associated fibroblasts for therapeutic delivery in desmoplastic tumors
The off-target distribution of anticancer nanoparticles to fibroblasts creates a barrier to the
effective treatment of desmoplastic tumors. However, we hypothesized that this nanoparticle …
effective treatment of desmoplastic tumors. However, we hypothesized that this nanoparticle …
Modulating the tumor microenvironment to enhance tumor nanomedicine delivery
B Zhang, Y Hu, Z Pang - Frontiers in pharmacology, 2017 - frontiersin.org
Nanomedicines including liposomes, micelles, and nanoparticles based on the enhanced
permeability and retention (EPR) effect have become the mainstream for tumor treatment …
permeability and retention (EPR) effect have become the mainstream for tumor treatment …
Targeted therapy of breast tumor by PLGA-based nanostructures: The versatile function in doxorubicin delivery
TS Dongsar, TT Dongsar, N Molugulu… - Environmental …, 2023 - Elsevier
Breast carcinoma is a molecularly diverse illness, and it is among the most prominent and
often reported malignancies in female across the globe. Surgical intervention …
often reported malignancies in female across the globe. Surgical intervention …
A nanomedicine structure–activity framework for research, development, and regulation of future cancer therapies
Despite their clinical success in drug delivery applications, the potential of theranostic
nanomedicines is hampered by mechanistic uncertainty and a lack of science-informed …
nanomedicines is hampered by mechanistic uncertainty and a lack of science-informed …