Multiscale label-free imaging of fibrillar collagen in the tumor microenvironment
With recent advances in cancer therapeutics, there is a great need for improved imaging
methods for characterizing cancer onset and progression in a quantitative and actionable …
methods for characterizing cancer onset and progression in a quantitative and actionable …
Hyperspectral imaging and dynamic region of interest tracking approaches to quantify localized cAMP signals
SC Johnson, NS Annamdevula… - Biochemical Society …, 2024 - portlandpress.com
Cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger known to
orchestrate a myriad of cellular functions over a wide range of timescales. In the last 20 …
orchestrate a myriad of cellular functions over a wide range of timescales. In the last 20 …
[HTML][HTML] Comparing performance of spectral image analysis approaches for detection of cellular signals in time-lapse hyperspectral imaging fluorescence excitation …
M Parker, NS Annamdevula, D Pleshinger, Z Ijaz… - Bioengineering, 2023 - mdpi.com
Hyperspectral imaging (HSI) technology has been applied in a range of fields for target
detection and mixture analysis. While HSI was originally developed for remote sensing …
detection and mixture analysis. While HSI was originally developed for remote sensing …
[HTML][HTML] Comparison of Whiskbroom and Pushbroom darkfield elastic light scattering spectroscopic imaging for head and neck cancer identification in a mouse model
MC Bassler, M Stefanakis, I Sequeira… - Analytical and …, 2021 - Springer
The early detection of head and neck cancer is a prolonged challenging task. It requires a
precise and accurate identification of tissue alterations as well as a distinct discrimination of …
precise and accurate identification of tissue alterations as well as a distinct discrimination of …
[HTML][HTML] Mucosal-Associated Invariant T Cells are not susceptible in vitro to SARS-CoV-2 infection but accumulate into the lungs of COVID-19 patients
X Huang, J Kantonen, K Nowlan, NA Nguyen… - Virus Research, 2024 - Elsevier
Prolonged T cell lymphopenia is common in COVID-19, caused by SARS-CoV-2. While the
mechanisms of lymphopenia during COVID-19 remain elusive, it is especially pronounced in …
mechanisms of lymphopenia during COVID-19 remain elusive, it is especially pronounced in …
Multifaceted mirror array illuminator for fluorescence excitation-scanning spectral imaging microscopy
M Parker, SA Mayes, CM Browning… - Journal of …, 2023 - spiedigitallibrary.org
Significance Hyperspectral imaging (HSI) technologies offer great potential in fluorescence
microscopy for multiplexed imaging, autofluorescence removal, and analysis of …
microscopy for multiplexed imaging, autofluorescence removal, and analysis of …
[HTML][HTML] Spectrofluorometric analysis of autofluorescing components of crude serum from a rat liver model of ischemia and reperfusion
Autofluorescence (AF) of crude serum was investigated with reference to the potential of its
intrinsic AF biomarkers for the noninvasive diagnosis of liver injury. Spectral parameters of …
intrinsic AF biomarkers for the noninvasive diagnosis of liver injury. Spectral parameters of …
Microscopy is better in color: development of a streamlined spectral light path for real-time multiplex fluorescence microscopy
CM Browning, S Mayes, SA Mayes, TC Rich… - Biomedical Optics …, 2022 - opg.optica.org
Spectroscopic image data has provided molecular discrimination for numerous fields
including: remote sensing, food safety and biomedical imaging. Despite the various …
including: remote sensing, food safety and biomedical imaging. Despite the various …
Development of an endothelial cell-restricted transgenic reporter rat: A resource for physiological studies of vascular biology
M Alexeyev, AM Geurts… - American Journal …, 2020 - journals.physiology.org
Here, we report the generation of a Cre-recombinase (iCre) transgenic rat, where iCre is
driven using a vascular endothelial-cadherin (CDH5) promoter. The CDH5 promoter was …
driven using a vascular endothelial-cadherin (CDH5) promoter. The CDH5 promoter was …
High-speed fluorescence excitation-scanning hyperspectral imaging microscopy using thin-film tunable filters
S Johnson, N Annamdevula, TC Rich… - … , and Analysis of …, 2024 - spiedigitallibrary.org
Hyperspectral imaging (HSI) technologies have enabled a range of experimental techniques
and studies in the fluorescence microscopy field. Unfortunately, a drawback of many HSI …
and studies in the fluorescence microscopy field. Unfortunately, a drawback of many HSI …