Detection, processing and reinforcement of social cues: regulation by the oxytocin system

R Menon, ID Neumann - Nature Reviews Neuroscience, 2023 - nature.com
Many social behaviours are evolutionarily conserved and are essential for the healthy
development of an individual. The neuropeptide oxytocin (OXT) is crucial for the fine-tuned …

Current and emerging methods for probing neuropeptide transmission

T Qian, H Wang, X Xia, Y Li - Current Opinion in Neurobiology, 2023 - Elsevier
Neuropeptides comprise the most diverse category of neurochemicals in the brain, playing
critical roles in a wide range of physiological and pathophysiological processes. Monitoring …

A tool kit of highly selective and sensitive genetically encoded neuropeptide sensors

H Wang, T Qian, Y Zhao, Y Zhuo, C Wu, T Osakada… - Science, 2023 - science.org
Neuropeptides are key signaling molecules in the endocrine and nervous systems that
regulate many critical physiological processes. Understanding the functions of …

Oxytocin receptors are widely distributed in the prairie vole (Microtus ochrogaster) brain: Relation to social behavior, genetic polymorphisms, and the dopamine …

K Inoue, CL Ford, K Horie… - Journal of Comparative …, 2022 - Wiley Online Library
Oxytocin regulates social behavior via direct modulation of neurons, regulation of neural
network activity, and interaction with other neurotransmitter systems. The behavioral effects …

[HTML][HTML] Social experience alters oxytocinergic modulation in the nucleus accumbens of female prairie voles

AM Borie, S Agezo, P Lunsford, AJ Boender, JD Guo… - Current Biology, 2022 - cell.com
Social relationships are dynamic and evolve with shared and personal experiences.
Whether the functional role of social neuromodulators also evolves with experience to shape …

Oxytocin receptors in the nucleus accumbens shell are necessary for the onset of maternal behavior

S Witchey, A Haupt, HK Caldwell - Frontiers in Neuroscience, 2024 - frontiersin.org
In rodents, oxytocin (Oxt) contributes to the onset of maternal care by shifting the perception
of pups from aversive to attractive. Both Oxt receptor knockout (Oxtr−/−) and forebrain …

The thalamic reticular nucleus orchestrates social memory

F Wang, H Sun, M Chen, B Feng, Y Lu, M Lyu, D Cui… - Neuron, 2024 - cell.com
Social memory has been developed in humans and other animals to recognize familiar
conspecifics and is essential for their survival and reproduction. Here, we demonstrated that …

Convergence of oxytocin and dopamine signaling in neuronal circuits: Insights into the neurobiology of social interactions across species

V Rappeneau, F Castillo-Díaz - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
Social behaviours are essential for animal survival, and the hypothalamic neuropeptide
oxytocin (OXT) critically impacts bonding, parenting, and decision-making. Dopamine (DA) …

[HTML][HTML] Recording and manipulation of the maternal oxytocin neural activities in mice

H Yukinaga, M Hagihara, K Tsujimoto, HL Chiang… - Current Biology, 2022 - cell.com
Pulsatile release of the hormone oxytocin (OT) mediates uterine contraction during
parturition and milk ejection during lactation. 1–3 These pulses are generated by the unique …

Neural basis for behavioral plasticity during the parental life-stage transition in mice

K Miyamichi - Frontiers in Neural Circuits, 2024 - frontiersin.org
Parental care plays a crucial role in the physical and mental well-being of mammalian
offspring. Although sexually naïve male mice, as well as certain strains of female mice …