Sepsis is defined as organ dysfunction resulting from the host's deleterious response to
infection. One of the most common organs affected is the kidneys, resulting in sepsis …

Sepsis occurs when an infection exceeds local tissue containment and induces a series of
dysregulated physiologic responses that result in organ dysfunction. A subset of patients …

Proprotein convertase subtilisin/kexin type 9 (PCSK9) plays an important role in the
regulation of cholesterol homeostasis. By binding to hepatic low-density lipoprotein (LDL) …

Rationale: Population studies suggest improved sepsis outcomes with statins, but the results
of randomized controlled trials in patients with sepsis and organ dysfunction in critical care …

There is an ongoing threat of epidemic or pandemic diseases that could be caused by
influenza, Ebola or other emerging viruses. It will be difficult and costly to develop new drugs …

Backgrounds & Aims There is a need to identify therapies that prevent the development of
acute-on-chronic liver failure (ACLF) in patients with cirrhosis. This study sought to evaluate …

Numerous studies have observed a decrease in total cholesterol, LDL-C, HDL-C, and
apolipoprotein B and AI levels in patients with COVID-19 infections, similar to what is …

Methods A literature search using keywords “statin” or “statins” combined with “minimum
inhibitory concentration”(MIC) was performed in six databases on 7th April 2017. After …

Background Dyslipidemia is a risk factor for cardiovascular disease, with elevated low-
density lipoprotein cholesterol (LDL-C) and decreased high-density lipoprotein cholesterol …

Despite the slow, progressive nature of NAFLD, the number of patients with NAFLD-related
cirrhosis has significantly increased. Although the management of patients with cirrhosis is …