Metabolic engineering advances and prospects for amino acid production
VF Wendisch - Metabolic engineering, 2020 - Elsevier
Amino acid fermentation is one of the major pillars of industrial biotechnology. The multi-
billion USD amino acid market is rising steadily and is diversifying. Metabolic engineering is …
billion USD amino acid market is rising steadily and is diversifying. Metabolic engineering is …
Pasteurella multocida pathogenesis:125 years after Pasteur
Pasteurella multocida was first shown to be the causative agent of fowl cholera by Louis
Pasteur in 1881. Since then, this Gram-negative bacterium has been identified as the …
Pasteur in 1881. Since then, this Gram-negative bacterium has been identified as the …
The live biotherapeutic SYNB1353 decreases plasma methionine via directed degradation in animal models and healthy volunteers
M Perreault, J Means, E Gerson, M James, S Cotton… - Cell Host & Microbe, 2024 - cell.com
Methionine is an essential proteinogenic amino acid, but its excess can lead to deleterious
effects. Inborn errors of methionine metabolism resulting from loss of function in …
effects. Inborn errors of methionine metabolism resulting from loss of function in …
Amino acid utilization allows intestinal dominance of Lactobacillus amylovorus
The mammalian intestine harbors heterogeneous distribution of microbes among which
specific taxa (eg Lactobacillus) dominate across mammals. Deterministic factors such as …
specific taxa (eg Lactobacillus) dominate across mammals. Deterministic factors such as …
Constructing gene co-expression networks and predicting functions of unknown genes by random matrix theory
Background Large-scale sequencing of entire genomes has ushered in a new age in
biology. One of the next grand challenges is to dissect the cellular networks consisting of …
biology. One of the next grand challenges is to dissect the cellular networks consisting of …
Why Is Carbonic Anhydrase Essential to Escherichia coli?
The can (previously yadF) gene of Escherichia coli encodes a β-class carbonic anhydrase
(CA), an enzyme which interconverts CO2 and bicarbonate. Various essential metabolic …
(CA), an enzyme which interconverts CO2 and bicarbonate. Various essential metabolic …
Canonical and ECF-type ATP-binding cassette importers in prokaryotes: diversity in modular organization and cellular functions
T Eitinger, DA Rodionov, M Grote… - FEMS microbiology …, 2011 - academic.oup.com
Since their discovery in the 1960s as 'osmotic shock-sensitive'transporters, a plethora of so-
called binding protein-dependent (canonical) ATP-binding cassette (ABC) importers has …
called binding protein-dependent (canonical) ATP-binding cassette (ABC) importers has …
[HTML][HTML] ATP-binding cassette transporters in Escherichia coli
A Moussatova, C Kandt, ML O'Mara… - Biochimica et Biophysica …, 2008 - Elsevier
ATP-binding cassette (ABC) transporters are integral membrane proteins that actively
transport molecules across cell membranes. In Escherichia coli they consist primarily of …
transport molecules across cell membranes. In Escherichia coli they consist primarily of …
The High-Affinity E. coli Methionine ABC Transporter: Structure and Allosteric Regulation
The crystal structure of the high-affinity Escherichia coli MetNI methionine uptake
transporter, a member of the adenosine triphosphate (ATP)–binding cassette (ABC) family …
transporter, a member of the adenosine triphosphate (ATP)–binding cassette (ABC) family …
Comparative genomics of the methionine metabolism in Gram-positive bacteria: a variety of regulatory systems
DA Rodionov, AG Vitreschak, AA Mironov… - Nucleic acids …, 2004 - academic.oup.com
Regulation of the methionine biosynthesis and transport genes in bacteria is rather diverse
and involves two RNA-level regulatory systems and at least three DNA-level systems. In …
and involves two RNA-level regulatory systems and at least three DNA-level systems. In …