[HTML][HTML] Neuroinflammation in cerebral ischemia and ischemia/reperfusion injuries: from pathophysiology to therapeutic strategies

A Jurcau, A Simion - International journal of molecular sciences, 2021 - mdpi.com
Its increasing incidence has led stroke to be the second leading cause of death worldwide.
Despite significant advances in recanalization strategies, patients are still at risk for …

[HTML][HTML] Neuroinflammation: friend and foe for ischemic stroke

RL Jayaraj, S Azimullah, R Beiram, FY Jalal… - Journal of …, 2019 - Springer
Stroke, the third leading cause of death and disability worldwide, is undergoing a change in
perspective with the emergence of new ideas on neurodegeneration. The concept that …

[HTML][HTML] Molecular pathophysiological mechanisms of ischemia/reperfusion injuries after recanalization therapy for acute ischemic stroke

A Jurcau, IA Ardelean - Journal of Integrative Neuroscience, 2021 - imrpress.com
With the larger variety of methods employed, recanalization therapy is increasingly used to
treat acute ischemic stroke resulting in about one-third of patients undergoing early …

Multistrain probiotics with Fructooligosaccharides improve middle cerebral artery occlusion–driven neurological deficits by revamping microbiota-gut-brain Axis

Z Rahman, NA Bhale, AG Dikundwar… - Probiotics and …, 2023 - Springer
Recent burgeoning literature unveils the importance of gut microbiota in the neuropathology
of post-stroke brain injury and recovery. Indeed, ingestion of prebiotics/probiotics imparts …

[HTML][HTML] Natural compounds for SIRT1-mediated oxidative stress and neuroinflammation in stroke: A potential therapeutic target in the future

C Fang, H Xu, L Yuan, Z Zhu, X Wang, Y Liu… - … Medicine and Cellular …, 2022 - hindawi.com
Stroke is a fatal cerebral vascular disease with a high mortality rate and substantial
economic and social costs. ROS production and neuroinflammation have been implicated in …

[HTML][HTML] Effects of early life stress on brain cytokines: A systematic review and meta-analysis of rodent studies

FS Lumertz, E Kestering-Ferreira, R Orso… - Neuroscience & …, 2022 - Elsevier
Exposure to early life stress (ELS) may lead to long-lasting neurobiological and behavioral
impairments. Alterations in the immune system and neuroinflammatory state induced by ELS …

Cellular and molecular influencers of neuroinflammation in Alzheimer's disease: recent concepts & roles

P Ghosh, R Singh, A Ganeshpurkar, AV Pokle… - Neurochemistry …, 2021 - Elsevier
Abstract Alzheimer's disease (AD), an extremely common neurodegenerative disorder of the
older generation, is one of the leading causes of death globally. Besides the conventional …

[HTML][HTML] Experimental pretreatment with chlorogenic acid prevents transient ischemia-induced cognitive decline and neuronal damage in the hippocampus through …

TK Lee, IJ Kang, B Kim, HJ Sim, DW Kim, JH Ahn… - Molecules, 2020 - mdpi.com
Chlorogenic acid (CGA), an ester of caffeic acid and quinic acid, is among the phenolic acid
compounds which can be naturally found in green coffee extract and tea. CGA has been …

Neuroprotective roles of Apelin-13 in neurological diseases

Y Zhang, W Jiang, W Sun, W Guo, B Xia, X Shen… - Neurochemical …, 2023 - Springer
Apelin is a natural ligand for the G protein-coupled receptor APJ, and the apelin/APJ system
is widely distributed in vivo. Among the apelin family, apelin-13 is the major apelin isoform in …

Small molecule inhibitors of NLRP3 inflammasome and GSK-3β in the management of traumatic brain injury: A review

MG Shaik, SV Joshi, R Akunuri, P Rana… - European Journal of …, 2023 - Elsevier
Traumatic brain injury (TBI) is a debilitating mental condition which causes physical
disability and morbidity worldwide. TBI may damage the brain by direct injury that …