Pharmaceutical product development is a challenging, time-consuming, and cost-intensive
process. Computational methods could be used for assistance and speed up the industrial …

Purpose: To investigate the impact of critical quality attributes (CQAs) and critical process
parameters (CPPs) on quality target product profile (QTPP) attributes of orally disintegrating …

Recent changes and limited resources for drug development and manufacturing have
rendered the conventional pharmaceutical quality assurance approach insufficient and have …

In this study, within the framework of Quality by Design which is a systematically scientific
approach which enables to understand and control the production and formulation variables …

Son yıllarda ilaç formülasyonu geliştirilmesinde deney tasarımı (DoE) kullanımı artmış
olmasına rağmen hala yeterli seviyede değildir. Özellikle katı ve yarı-katı dozaj formları gibi …

Bilayered oromucosal film preparations (buccal films) offer a promising way to enable drug
administration via the oral cavity. Polymeric film formulations containing chitosan, sodium …

ÖZET İlaç endüstrisi araştırma-geliştirme alanında, ürün kalitesini garantileyen ve ekipman
ile ham madde değişkenliklerini tolere edebilen sağlam bir işlem (proses) ve formülasyon …

Objectives: This design study was implemented within the scope of the quality by design
approach, which included the “International Conference on Harmonization” guidelines. We …

Objectives Orally disintegrating tablets (ODTs) can be utilized without any drinking water;
this feature makes ODTs easy to use and suitable for specific groups of patients. Oral …

Background: Conventional approach of formulating a new dosage form is a comprehensive
task and uses various sources like man, money, time and experimental efforts. The use of AI …