The measurement of quality indicators supports quality improvement initiatives. The German
Interdisciplinary Society of Intensive Care Medicine (DIVI) has published quality indicators …

Objectives: The current practice of therapeutic drug monitoring (TDM) in Asia is poorly
documented. Our aim was to capture and describe TDM services delivered in hospitals …

Various studies have reported insufficient beta-lactam concentrations in critically ill patients.
The optimal dosing strategy for beta-lactams in critically ill patients, particularly in septic …

In the antibacterial arsenal, β-lactams have held a prominent position, but increasing
resistance due to unauthorized use and genetic factors requires new strategies. Combining …

„Dosis sola facit venenum “, allein die Dosis macht das Gift, so die pragmatische
Übersetzung des berühmten Lehrsatzes des Theophrastus Bombast von Hohenheim …

多重耐药革兰阴性菌感染的危重症患者, 因个体间药动学(PK) 参数差异较大,
接受说明书推荐给药剂量的3 内酰胺类抗菌药物治疗, 其药动学/药效学(pharmacodynamics …

objetivo: Fornecer informações sobre as principais alterações fisiológicas que podem
influenciar as propriedades farmacológicas em pacientes críticos e das interações …

Although the measurement of aminoglycosides and glycopeptides in blood has been well
established, it has become evident that therapeutic drug monitoring (TDM) should be …

For many years, the definition of appropriate anti-infective therapy has relied on the concept
of timely commencement of drug treatment with the spectrum appropriate for the pathogen …

Adequate antibiotic therapy for critically ill intensive care patients is a daily challenge. In
addition to the timely selection and application of the right substance, pharmacokinetic and …