Horizontal transfer of antibiotic resistance genes in clinical environments

NA Lerminiaux, ADS Cameron - Canadian journal of …, 2019 - cdnsciencepub.com
A global medical crisis is unfolding as antibiotics lose effectiveness against a growing
number of bacterial pathogens. Horizontal gene transfer (HGT) contributes significantly to …

NDM metallo-β-lactamases and their bacterial producers in health care settings

W Wu, Y Feng, G Tang, F Qiao… - Clinical microbiology …, 2019 - Am Soc Microbiol
New Delhi metallo-β-lactamase (NDM) is a metallo-β-lactamase able to hydrolyze almost all
β-lactams. Twenty-four NDM variants have been identified in> 60 species of 11 bacterial …

[HTML][HTML] Extended-spectrum β-lactamase-producing and carbapenemase-producing Enterobacteriaceae

H Wilson, ME Török - Microbial genomics, 2018 - microbiologyresearch.org
Antimicrobial resistance (AMR) is a global public-health emergency, which threatens the
advances made by modern medical care over the past century. The World Health …

Coproduction Of MCR-9 And NDM-1 By Colistin-Resistant Enterobacter hormaechei Isolated From Bloodstream Infection

Y Yuan, Y Li, G Wang, C Li, L Xiang, J She… - Infection and drug …, 2019 - Taylor & Francis
Background Colistin acts as the last line of defense against severe infections caused by
carbapenem-resistant Enterobacteriaceae. Infections caused by extensively drug-resistant …

[HTML][HTML] Rapid, multiplexed, whole genome and plasmid sequencing of foodborne pathogens using long-read nanopore technology

TL Taylor, JD Volkening, E DeJesus, M Simmons… - Scientific reports, 2019 - nature.com
US public health agencies have employed next-generation sequencing (NGS) as a tool to
quickly identify foodborne pathogens during outbreaks. Although established short-read …

The genomic characterization of carbapenem-resistant Serratia marcescens at a tertiary hospital in South Africa

AJ Overmeyer, E Prentice, A Brink… - JAC-Antimicrobial …, 2023 - academic.oup.com
Background Serratia marcescens is an opportunistic nosocomial pathogen, and recent
reports have highlighted the rapid increase in multidrug resistance in this organism. There is …

[HTML][HTML] Characterization of KPC-Producing Serratia marcescens in an Intensive Care Unit of a Brazilian Tertiary Hospital

RL Ferreira, GS Rezende, MSF Damas… - Frontiers in …, 2020 - frontiersin.org
Serratia marcescens has emerged as an important opportunistic pathogen responsible for
nosocomial and severe infections. Here, we determined phenotypic and molecular …

[HTML][HTML] Rapid virulence prediction and identification of Newcastle disease virus genotypes using third-generation sequencing

SL Butt, TL Taylor, JD Volkening, KM Dimitrov… - Virology journal, 2018 - Springer
Background Newcastle disease (ND) outbreaks are global challenges to the poultry
industry. Effective management requires rapid identification and virulence prediction of the …

Occurrence and characterization of Escherichia coli ST410 co-harbouring blaNDM-5, blaCMY-42 and blaTEM-190 in a dog from the UK

ME Reynolds, HTT Phan, S George… - Journal of …, 2019 - academic.oup.com
Abstract Background/Objectives Carbapenemase-producing Enterobacteriaceae (CPE) are
a public health threat, and have been found in humans, animals and the environment …

[HTML][HTML] Detection and characterisation of 16S rRNA methyltransferase-producing Pseudomonas aeruginosa from the UK and Republic of Ireland from 2003–2015

E Taylor, E Jauneikaite, S Sriskandan… - International Journal of …, 2022 - Elsevier
ABSTRACT 16S rRNA methyltransferase (16S RMTase) genes confer high-level
aminoglycoside resistance, reducing treatment options for multidrug-resistant Gram …