Renal cystic diseases: a review

M Bisceglia, CA Galliani, C Senger… - Advances in anatomic …, 2006 - journals.lww.com
This review aims to assist in the categorization of inherited, developmental, and acquired
cystic disease of the kidney as well as to provide a pertinent, up-to-date bibliography. The …

Calcium signalling during embryonic development

SE Webb, AL Miller - Nature reviews Molecular cell biology, 2003 - nature.com
Consider a hypothetical design specification for an integrated communication-control system
within an embryo. It would require short-range (subcellular) and long-range (pan-embryonic) …

Polycystin 2 interacts with type I inositol 1, 4, 5-trisphosphate receptor to modulate intracellular Ca2+ signaling

Y Li, JM Wright, F Qian, GG Germino… - Journal of Biological …, 2005 - ASBMB
Autosomal dominant polycystic kidney disease, a common cause of renal failure, arises from
mutations in either the PKD1 or the PKD2 gene. The precise function of both PKD gene …

Pathobiology of human cerebrovascular malformations: basic mechanisms and clinical relevance

J Gault, H Sarin, NA Awadallah, R Shenkar… - Neurosurgery, 2004 - journals.lww.com
Abstract CEREBROVASCULAR MALFORMATIONS AFFECT more than 3% of the
population, exposing them to a lifetime risk of hemorrhagic stroke, seizures, and focal …

Cerebral cavernous malformation: new molecular and clinical insights

N Revencu, M Vikkula - Journal of medical genetics, 2006 - jmg.bmj.com
Cerebral cavernous malformation (CCM) is a vascular malformation causing neurological
problems, such as headaches, seizures, focal neurological deficits, and cerebral …

Renal cystic neoplasms and renal neoplasms associated with cystic renal diseases: pathogenetic and molecular links

LD Truong, YJ Choi, SS Shen, G Ayala… - Advances in anatomic …, 2003 - journals.lww.com
Cystic renal neoplasms represent an isolated cystic mass not accompanied by cystic change
of the renal parenchyma. Although cystic change may be seen in any type of renal …

Low high-density lipoprotein cholesterol: physiological background, clinical importance and drug treatment

M Hersberger, A Eckardstein - Drugs, 2003 - Springer
Low high-density lipoprotein (HDL) cholesterol is an important risk factor for coronary heart
disease (CHD). In vitro, HDL exerts several potentially anti-atherogenic activities. HDLs …

[HTML][HTML] TRPP2 and autosomal dominant polycystic kidney disease

M Köttgen - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2007 - Elsevier
Mutations in TRPP2 (polycystin-2) cause autosomal dominant polycystic kidney disease
(ADPKD), a common genetic disorder characterized by progressive development of fluid …

Polycystin-1 interacts with inositol 1, 4, 5-trisphosphate receptor to modulate intracellular Ca2+ signaling with implications for polycystic kidney disease

Y Li, NG Santoso, S Yu, OM Woodward, F Qian… - Journal of Biological …, 2009 - ASBMB
The PKD1 or PKD2 genes encode polycystins (PC) 1 and 2, which are associated with
polycystic kidney disease. Previously we demonstrated that PC2 interacts with the inositol 1 …

Virtual-tissue computer simulations define the roles of cell adhesion and proliferation in the onset of kidney cystic disease

JM Belmonte, SG Clendenon, GM Oliveira… - Molecular biology of …, 2016 - Am Soc Cell Biol
In autosomal dominant polycystic kidney disease (ADPKD), cysts accumulate and
progressively impair renal function. Mutations in PKD1 and PKD2 genes are causally linked …