Monocytes, macrophages, and metabolic disease in atherosclerosis
Atherosclerotic cardiovascular disease (CVD) is a lipid-driven chronic inflammatory disease,
in which macrophages are responsible for taking up these lipids and driving disease …
in which macrophages are responsible for taking up these lipids and driving disease …
Myeloid-derived suppressor cells: ductile targets in disease
FM Consonni, C Porta, A Marino, C Pandolfo… - Frontiers in …, 2019 - frontiersin.org
Myeloid-derived suppressor cells (MDSCs) represent a heterogeneous population of
immature myeloid cells with major regulatory functions and rise during pathological …
immature myeloid cells with major regulatory functions and rise during pathological …
Translation of cell therapies to treat autoimmune disorders
Autoimmune diseases are a diverse and complex set of chronic disorders with a substantial
impact on patient quality of life and a significant global healthcare burden. Current …
impact on patient quality of life and a significant global healthcare burden. Current …
Myeloid-derived suppressor cells (MDSC): When good intentions go awry
MD Sanchez-Pino, MJ Dean, AC Ochoa - Cellular immunology, 2021 - Elsevier
MDSC are a heterogeneous population of immature myeloid cells that are released by
biological stress such as tissue damage and inflammation. Conventionally, MDSC are …
biological stress such as tissue damage and inflammation. Conventionally, MDSC are …
Mitochondrial DNA activates the NLRP3 inflammasome and predisposes to type 1 diabetes in murine model
Although a correlation between polymorphisms of NOD-like receptor family-pyrin domain
containing 3 (NLRP3) and predisposition to type 1 diabetes (T1D) has been identified, the …
containing 3 (NLRP3) and predisposition to type 1 diabetes (T1D) has been identified, the …
Emerging roles of myeloid-derived suppressor cells in diabetes
S Wang, Q Tan, Y Hou, H Dou - Frontiers in Pharmacology, 2021 - frontiersin.org
Diabetes is a syndrome characterized by hyperglycemia with or without insulin resistance.
Its etiology is attributed to the combined action of genes, environment and immune cells …
Its etiology is attributed to the combined action of genes, environment and immune cells …
MDSCs, ageing and inflammageing
The challenge of distinguishing between changes attributable to ageing and those
attributable to pathology is even greater for the immune system than for many other organs …
attributable to pathology is even greater for the immune system than for many other organs …
Myeloid derived suppressor cells and autoimmunity
Myeloid-derived suppressor cells are a heterogeneous group of immature myeloid cells with
immunoregulatory function. When activated and expanded, these cells can suppress T cell …
immunoregulatory function. When activated and expanded, these cells can suppress T cell …
Myeloid‐derived suppressor cells in the therapy of autoimmune diseases
Myeloid‐derived suppressor cells (MDSCs) are well recognized as critical factors in the
pathology of tumors. However, their roles in autoimmune diseases are still unclear, which …
pathology of tumors. However, their roles in autoimmune diseases are still unclear, which …
[HTML][HTML] MDA5-dependent responses contribute to autoimmune diabetes progression and hindrance
SI Blum, JP Taylor, JM Barra, AR Burg, Q Shang… - JCI insight, 2023 - ncbi.nlm.nih.gov
Abstract Type 1 diabetes (T1D) is an autoimmune disease resulting in pancreatic β cell
destruction. Coxsackievirus B3 (CVB3) infection and melanoma differentiation-associated …
destruction. Coxsackievirus B3 (CVB3) infection and melanoma differentiation-associated …