Inhaled drug treatment for tuberculosis: Past progress and future prospects

AJ Hickey, PG Durham, A Dharmadhikari… - Journal of Controlled …, 2016 - Elsevier
Since the 1990s the rising incidence of multiple drug resistant TB, particularly in the context
of human immunodeficiency virus co-infected patients, has threatened global TB control. At …

Fluorometric imaging methods for palladium and platinum and the use of palladium for imaging biomolecules

MP Tracey, D Pham, K Koide - Chemical Society Reviews, 2015 - pubs.rsc.org
Neither palladium nor platinum is an endogenous biological metal. Imaging palladium in
biological samples, however, is becoming increasingly important because bioorthogonal …

[HTML][HTML] Co-delivery of cisplatin and paclitaxel by folic acid conjugated amphiphilic PEG-PLGA copolymer nanoparticles for the treatment of non-small lung cancer

Z He, J Huang, Y Xu, X Zhang, Y Teng, C Huang… - Oncotarget, 2015 - ncbi.nlm.nih.gov
An amphiphilic copolymer, folic acid (FA) modified poly (ethylene glycol)-poly (lactic-co-
glycolic acid)(FA-PEG-PLGA) was prepared and explored as a nanometer carrier for the co …

The protective effect of albumin on bevacizumab activity and stability in PLGA nanoparticles intended for retinal and choroidal neovascularization treatments

R Varshochian, M Jeddi-Tehrani, AR Mahmoudi… - European Journal of …, 2013 - Elsevier
The rapidly growing applications of antibody-based therapeutics requires novel approaches
to develop efficient drug delivery systems in which biodegradable polymeric nanoparticles …

Development of porous particles using dextran as an excipient for enhanced deep lung delivery of rifampicin

K Kadota, Y Yanagawa, T Tachikawa, Y Deki… - International journal of …, 2019 - Elsevier
This study aimed to develop a dry powder inhaler (DPI) formulation for enhanced deep lung
delivery of rifampicin using dextrans of different molecular weights. Porous particles were …

Meeting the unmet: from traditional to cutting-edge techniques for poly lactide and poly lactide-co-glycolide microparticle manufacturing

A Schoubben, M Ricci, S Giovagnoli - Journal of Pharmaceutical …, 2019 - Springer
Background Polylactides (PLA) and poly lactide-co-glycolides (PLGA) undoubtedly are
among the major drivers in the pharmaceutical market. Their relevance in pharmaceutics …

Engineering porous PLGA microparticles for pulmonary delivery of sildenafil citrate

REL Lazo, B de Paula Oliveira, A de Fátima Cobre… - Powder Technology, 2023 - Elsevier
Orally administered Sildenafil (SDF) is used to treat pulmonary arterial hypertension.
However, it has a relatively low bioavailability of approximately 40%. To circumvent such …

A particle technology approach toward designing dry-powder inhaler formulations for personalized medicine in respiratory diseases

K Kadota, TR Sosnowski, S Tobita, I Tachibana… - Advanced Powder …, 2020 - Elsevier
Compared with oral and parenteral formulations, inhaled formulations are attractive because
of their great benefit and potential to enhance therapeutic effects of medications. Among the …

Nanomedicines as drug delivery carriers of anti-tubercular drugs: from pathogenesis to infection control

A Hussain, S Singh, SS Das, K Anjireddy… - Current Drug …, 2019 - ingentaconnect.com
In spite of advances in tuberculosis (TB) chemotherapy, TB is still airborne deadly disorder
as a major issue of health concern worldwide today. Extensive researches have been …

[HTML][HTML] Particles from preformed polymers as carriers for drug delivery

K Miladi, D Ibraheem, M Iqbal, S Sfar, H Fessi… - EXCLI …, 2014 - ncbi.nlm.nih.gov
Biodegradable and biocompatible polymers are widely used for the encapsulation of drug
molecules. Various particulate carriers with different sizes and characteristics have been …