Mechanical signalling affects multiple biological processes during development and in adult
organisms, including cell fate transitions, cell migration, morphogenesis and immune …

Peritoneal fibrosis is characterized by abnormal production of extracellular matrix proteins
leading to progressive thickening of the submesothelial compact zone of the peritoneal …

Gonadal development is a complex process that involves sex determination followed by
divergent maturation into either testes or ovaries. Historically, limited tissue accessibility, a …

Advanced ovarian cancers are highly metastatic due to frequent peritoneal dissemination,
resulting in dismal prognosis. Here we report the functions of cancer-derived extracellular …

Epithelial–mesenchymal transition (EMT) is a reversible cellular process, characterized by
changes in gene expression and activation of proteins, favoring the trans-differentiation of …

Mechanical forces (extracellular matrix stiffness, vascular shear stress, and muscle
stretching) reaching the plasma membrane (PM) determine cell behavior. Caveolae are PM …

Over the past decade, interest in caveolae biology has peaked. These small bulb-shaped
plasma membrane invaginations of 50–80 nm diameter present in most cell types have …

Peritoneal dialysis (PD) is an efficient renal replacement therapy for patients with end-stage
renal disease. Even if it ensures an outcome equivalent to hemodialysis and a better quality …

Rationale: Maintaining endothelial cells (EC) as a monolayer in the vessel wall depends on
their metabolic state and gene expression profile, features influenced by contact with …

Peritoneal dialysis is a form of renal replacement alternative to the hemodialysis. During this
treatment, the peritoneal membrane acts as a permeable barrier for exchange of solutes and …