Cyclodextrin based natural nanostructured carbohydrate polymers as effective non-viral siRNA delivery systems for cancer gene therapy

H Mousazadeh, Y Pilehvar-Soltanahmadi… - Journal of Controlled …, 2021 - Elsevier
Short interfering RNAs (siRNAs), as small non-coding RNA fragments, are one of the widely
studied RNAi inducers for gene modulations. The reasonably designed siRNA probes …

Cyclodextrin-based polymer materials: from controlled synthesis to applications

X Yao, P Huang, Z Nie - Progress in Polymer Science, 2019 - Elsevier
The design and construction of polymers with diverse architectures play an important role in
the field of polymer science and offers new opportunities for the development of novel …

Cyclodextrins in drug delivery: applications in gene and combination therapy

RM Haley, R Gottardi, R Langer, MJ Mitchell - Drug delivery and …, 2020 - Springer
Gene therapy is a powerful tool against genetic disorders and cancer, targeting the source of
the disease rather than just treating the symptoms. While much of the initial success of gene …

Polycyclodextrins: Synthesis, functionalization, and applications

F Seidi, Y Jin, H Xiao - Carbohydrate polymers, 2020 - Elsevier
Cyclodextrins (CDs) are cyclic oligosaccharides with unique conical structure enabling host-
guest inclusion complexes. However, virgin CDs sufferfrom low solubility, lack of functional …

Wholly Visible-Light-Responsive Host–Guest Supramolecular Gels Based on Methoxy Azobenzene and β-Cyclodextrin Dimers

H Yan, Y Qiu, J Wang, Q Jiang, H Wang, Y Liao, X Xie - Langmuir, 2020 - ACS Publications
Much attention has been paid to construct photoresponsive host–guest supramolecular gels;
however, red-shifting the responsive wavelength remains a formidable challenge. Here, a …

[HTML][HTML] Recent advances in the application of ATRP in the synthesis of drug delivery systems

M Szewczyk-Łagodzińska, A Plichta, M Dębowski… - Polymers, 2023 - mdpi.com
Advances in atom transfer radical polymerization (ATRP) have enabled the precise design
and preparation of nanostructured polymeric materials for a variety of biomedical …

Functional materials generated by allying cyclodextrin-based supramolecular chemistry with living polymerization

F Seidi, AA Shamsabadi, M Amini, M Shabanian… - Polymer …, 2019 - pubs.rsc.org
Cyclodextrin molecules are cyclic oligosaccharides that display a unique structure including
an inner side and two faces on their outer sides. Each face and the inner core can be …

Current status of ATRP-based materials for gene therapy

S de Ávila Gonçalves, RP Vieira - Reactive and Functional Polymers, 2020 - Elsevier
Gene therapy is an auspicious alternative to treat diseases. However, the design of efficient
vectors remains as a challenge due to the innumerous intracellular and extracellular barriers …

[HTML][HTML] Hyper-branched cationic cyclodextrin polymers for improving plasmid transfection in 2D and 3D spheroid cells

YK Monfared, M Mahmoudian, C Cecone, F Caldera… - Pharmaceutics, 2022 - mdpi.com
In this article, we used monolayer two dimensional (2D) and 3D multicellular spheroid
models to improve our understanding of the gene delivery process of a new modified …

[HTML][HTML] An Overview of the Supramolecular Systems for Gene and Drug Delivery in Tissue Regeneration

SR Ranamalla, AS Porfire, I Tomuță, M Banciu - Pharmaceutics, 2022 - mdpi.com
Tissue regeneration is a prominent area of research, developing biomaterials aimed to be
tunable, mechanistic scaffolds that mimic the physiological environment of the tissue. These …