It is estimated that more than 339 million people worldwide suffer from asthma. The leading
cause of asthma development is the breakdown of immune tolerance to inhaled allergens …

Allergy is a major public health problem with a high socio‐economic impact. The number of
allergic patients is expected to reach to four billion within two decades when the World's …

Before the first description of hay fever in 1870, there was very little awareness of allergic
disease, which is actually similar to the situation in prehygiene villages in Africa today. The …

The house dust mite (HDM) is a major perennial allergen source and a significant cause of
allergic rhinitis and allergic asthma. However, awareness of the condition remains generally …

Dietary and bacterial metabolites influence immune responses. This raises the question
whether the increased incidence of allergies, asthma, some autoimmune diseases …

Advancing our understanding of mechanisms of immune regulation in allergy, asthma,
autoimmune diseases, tumor development, organ transplantation, and chronic infections …

Background Wheezing illnesses cause major morbidity in infants and are frequent
precursors to asthma. Objective We sought to examine environmental factors associated …

Background The evolution of the IgE response to the numerous allergen molecules of
Dermatophagoides pteronyssinus is still unknown. Objectives We sought to characterize the …

Allergic rhinitis is a symptomatic disorder of the nose induced after allergen exposure by an
immunoglobulin E (IgE)-mediated inflammation of the membranes lining the nose (1). It was …

Immune tolerance to both self-antigens and innocuous non–self-antigens is essential to
protect the host against chronic inflammatory diseases and tissue damage. A wide range of …