Immunomodulation by mesenchymal stem cells (MSCs): mechanisms of action of living, apoptotic, and dead MSCs
ARR Weiss, MH Dahlke - Frontiers in immunology, 2019 - frontiersin.org
Expectations on mesenchymal stem cell (MSC) treatment are high, especially in the fields of
sepsis, transplant medicine, and autoimmune diseases. Various pre-clinical studies have …
sepsis, transplant medicine, and autoimmune diseases. Various pre-clinical studies have …
Immunomodulatory and regenerative effects of mesenchymal stem cells and extracellular vesicles: therapeutic outlook for inflammatory and degenerative diseases
S Dabrowska, A Andrzejewska, M Janowski… - Frontiers in …, 2021 - frontiersin.org
Mesenchymal stem cells (MSCs) are non-hematopoietic, multipotent stem cells derived from
mesoderm, which can be easily isolated from many sources such as bone marrow, umbilical …
mesoderm, which can be easily isolated from many sources such as bone marrow, umbilical …
Mesenchymal stromal cell homing: mechanisms and strategies for improvement
Mesenchymal stromal cells (MSCs) have been widely investigated for their therapeutic
potential in regenerative medicine, owing to their ability to home damaged tissue and serve …
potential in regenerative medicine, owing to their ability to home damaged tissue and serve …
Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation
A Galleu, Y Riffo-Vasquez, C Trento, C Lomas… - Science translational …, 2017 - science.org
The immunosuppressive activity of mesenchymal stromal cells (MSCs) is well documented.
However, the therapeutic benefit is completely unpredictable, thus raising concerns about …
However, the therapeutic benefit is completely unpredictable, thus raising concerns about …
[HTML][HTML] Intranasal delivery of BDNF-loaded small extracellular vesicles for cerebral ischemia therapy
X Zhou, X Deng, M Liu, M He, W Long, Z Xu… - Journal of Controlled …, 2023 - Elsevier
Mesenchymal stem cells (MSCs) have shown promise for the therapy of cerebral ischemia in
animal studies and clinical trials, yet their clinical application still faces many challenges …
animal studies and clinical trials, yet their clinical application still faces many challenges …
Mesenchymal stem cells and immunomodulation: current status and future prospects
F Gao, SM Chiu, DAL Motan, Z Zhang, L Chen… - Cell death & …, 2016 - nature.com
The unique immunomodulatory properties of mesenchymal stem cells (MSCs) make them
an invaluable cell type for the repair of tissue/organ damage caused by chronic inflammation …
an invaluable cell type for the repair of tissue/organ damage caused by chronic inflammation …
Impact of cryopreservation and freeze-thawing on therapeutic properties of mesenchymal stromal/stem cells and other common cellular therapeutics
C Cottle, AP Porter, A Lipat, C Turner-Lyles… - Current stem cell …, 2022 - Springer
Abstract Purpose of Review Cryopreservation and its associated freezing and thawing
procedures–short “freeze-thawing”–are among the final steps in economically viable …
procedures–short “freeze-thawing”–are among the final steps in economically viable …
Mesenchymal stem cell therapy for the treatment of inflammatory diseases: challenges, opportunities, and future perspectives
Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …
Mesenchymal stem cells: immune evasive, not immune privileged
The diverse immunomodulatory properties of mesenchymal stem/stromal cells (MSCs) may
be exploited for treatment of a multitude of inflammatory conditions. MSCs have long been …
be exploited for treatment of a multitude of inflammatory conditions. MSCs have long been …
[HTML][HTML] Homing and migration of mesenchymal stromal cells: how to improve the efficacy of cell therapy?
A De Becker, I Van Riet - World journal of stem cells, 2016 - ncbi.nlm.nih.gov
Mesenchymal stromal cells (MSCs) are currently being investigated for use in a wide variety
of clinical applications. For most of these applications, systemic delivery of the cells is …
of clinical applications. For most of these applications, systemic delivery of the cells is …