Candida albicans-Biology, molecular characterization, pathogenicity, and advances in diagnosis and control–An update

M Dadar, R Tiwari, K Karthik, S Chakraborty… - Microbial …, 2018 - Elsevier
Candida albicans is an emerging multidrug-resistant fungal pathogen representing an
important source of invasive disease in humans and generating high healthcare costs …

Moonlighting proteins at the candidal cell surface

D Satala, J Karkowska-Kuleta, A Zelazna… - Microorganisms, 2020 - mdpi.com
The cell wall in Candida albicans is not only a tight protective envelope but also a point of
contact with the human host that provides a dynamic response to the constantly changing …

Membrane receptor-mediated mechano-transduction maintains cell integrity during pollen tube growth within the pistil

X Zhou, J Lu, Y Zhang, J Guo, W Lin, JM Van Norman… - Developmental Cell, 2021 - cell.com
Invasive or penetrative growth is critical for developmental and reproductive processes (eg,
pollen tube penetration of pistils) and disease progression (eg, cancer metastasis and …

Comparative genomics reveals the origin of fungal hyphae and multicellularity

E Kiss, B Hegedüs, M Virágh, T Varga… - Nature …, 2019 - nature.com
Hyphae represent a hallmark structure of multicellular fungi. The evolutionary origins of
hyphae and of the underlying genes are, however, hardly known. By systematically …

Multiple alternative carbon pathways combine to promote Candida albicans stress resistance, immune interactions, and virulence

RB Williams, MC Lorenz - MBio, 2020 - Am Soc Microbiol
The phagocytic cells of the innate immune system are an essential first line of antimicrobial
defense, and yet Candida albicans, one of the most problematic fungal pathogens, is …

Candida albicans hyphal extracellular vesicles are different from yeast ones, carrying an active proteasome complex and showing a different role in host immune …

R Martínez-López, ML Hernáez, E Redondo… - Microbiology …, 2022 - Am Soc Microbiol
Candida albicans is the principal causative agent of lethal fungal infections, predominantly
in immunocompromised hosts. Extracellular vesicles (EVs) have been described as crucial …

Candida albicans and Pseudomonas aeruginosa Interaction, with Focus on the Role of Eicosanoids

R Fourie, R Ells, CW Swart, OM Sebolai… - Frontiers in …, 2016 - frontiersin.org
Candida albicans is commonly found in mixed infections with Pseudomonas aeruginosa,
especially in the lungs of cystic fibrosis (CF) patients. Both of these opportunistic pathogens …

Extracellular vesicle-associated transitory cell wall components and their impact on the interaction of fungi with host cells

L Nimrichter, MM De Souza, M Del Poeta… - Frontiers in …, 2016 - frontiersin.org
Classic cell wall components of fungi comprise the polysaccharides glucans and chitin, in
association with glycoproteins and pigments. During the last decade, however, system …

Global proteomic analysis deciphers the mechanism of action of plant derived oleic acid against Candida albicans virulence and biofilm formation

S Muthamil, KG Prasath, A Priya, P Precilla… - Scientific reports, 2020 - nature.com
Candida albicans is a commensal fungus in humans, mostly found on the mucosal surfaces
of the mouth, gut, vagina and skin. Incidence of ever increasing invasive candidiasis in …

Robust extracellular pH modulation by Candida albicans during growth in carboxylic acids

HA Danhof, S Vylkova, EM Vesely, AE Ford… - MBio, 2016 - Am Soc Microbiol
The opportunistic fungal pathogen Candida albicans thrives within diverse niches in the
mammalian host. Among the adaptations that underlie this fitness is an ability to utilize a …