Recent advances in cardiac SPECT instrumentation and imaging methods

J Wu, C Liu - Physics in Medicine & Biology, 2019 - iopscience.iop.org
Cardiac SPECT continues to play a critical role in detecting and managing cardiovascular
disease, in particularly coronary artery disease (CAD)(Jaarsma et al 2012 J. Am. Coll …

[HTML][HTML] Quantitative SPECT: the time is now

J Dickson, J Ross, S Vöö - EJNMMI physics, 2019 - Springer
Background Quantification is one of the key benefits of nuclear medicine imaging. Recently,
driven by the demand for post radionuclide therapy imaging, quantitative SPECT has moved …

[HTML][HTML] Navigating new horizons: Prospects of NET-targeted radiopharmaceuticals in precision medicine

T Higuchi, X Chen, RA Werner - Theranostics, 2024 - ncbi.nlm.nih.gov
In the evolving landscape of precision medicine, NET-targeted radiopharmaceuticals are
emerging as pivotal tools for the diagnosis and treatment of a range of conditions, from heart …

[HTML][HTML] Image quantification for TSPO PET with a novel image-derived input function method

YHD Fang, JE McConathy, TA Yacoubian, Y Zhang… - Diagnostics, 2022 - mdpi.com
There is a growing interest in using 18F-DPA-714 PET to study neuroinflammation and
microglial activation through imaging the 18-kDa translocator protein (TSPO). Although …

F-18 meta-fluorobenzylguanidine PET imaging of myocardial sympathetic innervation

M Grkovski, PB Zanzonico, S Modak, JL Humm… - Journal of Nuclear …, 2022 - Elsevier
Abstract Background I-123 meta-iodobenzylguanidine (MIBG) imaging has long been
employed to noninvasively assess the integrity of human norepinephrine transporter-1 and …

[18F] MFBG PET imaging: biodistribution, pharmacokinetics, and comparison with [123I] MIBG in neural crest tumour patients

E Pauwels, S Celen, K Baete, M Koole… - European Journal of …, 2023 - Springer
Purpose Despite its limitations,[123I] MIBG scintigraphy has been the standard for human
norepinephrine transporter (hNET) imaging for several decades. Recently,[18F] MFBG has …

[HTML][HTML] Analysis of quantitative [I-123] mIBG SPECT/CT in a phantom and in patients with neuroblastoma

SL Brady, BL Shulkin - EJNMMI physics, 2019 - Springer
Purpose To determine the accuracy of quantitative SPECT, intersystem and interpatient
standardized uptake value (SUV) calculation consistency for a manufacturer-independent …

Ventricular arrhythmia substrate distribution and its relation to sympathetic innervation in nonischemic cardiomyopathy patients

HS Chen, C Jungen, Y Kimura… - Clinical …, 2022 - jacc.org
Background Nonischemic cardiomyopathy patients referred for catheter ablation of
ventricular arrhythmias (VAs) typically have either inferolateral (ILS) or anteroseptal (ASS) …

Noise suppressed partial volume correction for cardiac SPECT/CT

C Chan, H Liu, Y Grobshtein, MR Stacy… - Medical …, 2016 - Wiley Online Library
Purpose: Partial volume correction (PVC) methods typically improve quantification at the
expense of increased image noise and reduced reproducibility. In this study, the authors …

Feasibility study of PET dynamic imaging of [18F] DHMT for quantification of reactive oxygen species in the myocardium of large animals

J Wu, NE Boutagy, Z Cai, S Lin, MQ Zheng… - Journal of Nuclear …, 2022 - Elsevier
Objectives We aimed to develop a dynamic imaging technique for a novel PET superoxide
tracer,[18 F] DHMT, to allow for absolute quantification of myocardial reactive oxygen …