Pathophysiology of type 2 diabetes in sub-Saharan Africans

JH Goedecke, AE Mendham - Diabetologia, 2022 - Springer
Abstract Sub-Saharan Africa (SSA) is the region with the highest projected rates of increase
in type 2 diabetes (129% by 2045), which will exacerbate the already high prevalence of …

Alcohol consumption patterns: a systematic review of demographic and sociocultural influencing factors

AA Khamis, SZ Salleh, MS Ab Karim… - International Journal of …, 2022 - mdpi.com
Background: Excessive alcohol consumption has negative effects not only on the drinkers'
health but also on others around them. Previous studies suggest that excessive alcohol …

Carotid atherosclerosis, microalbuminuria, and estimated 10-year atherosclerotic cardiovascular disease risk in Sub-Saharan Africa

EA Nonterah, D Boateng, NJ Crowther… - JAMA network …, 2022 - jamanetwork.com
Importance Carotid atherosclerosis and microalbuminuria are associated with
atherosclerotic cardiovascular disease (ASCVD) but are understudied in sub-Saharan …

Identifying the prevalence and correlates of multimorbidity in middle-aged men and women: a cross-sectional population-based study in four African countries

LK Micklesfield, R Munthali, G Agongo, G Asiki… - BMJ open, 2023 - bmjopen.bmj.com
Objectives To determine the prevalence of multimorbidity, to identify which chronic
conditions cluster together and to identify factors associated with a greater risk for …

Association between socio-economic status and non-communicable disease risk in young adults from Kenya, South Africa, and the United Kingdom

A Mtintsilana, A Craig, W Mapanga, SN Dlamini… - Scientific Reports, 2023 - nature.com
There is a pressing need for global health preventions to curb the escalating burden of non-
communicable diseases (NCDs). Utilising multi-country study designs can improve our …

Prevalence and correlates of common mental disorders among participants of the Uganda Genome Resource: Opportunities for psychiatric genetics research

A Kalungi, E Kinyanda, DH Akena, B Gelaye… - Molecular …, 2024 - nature.com
Genetics research has potential to alleviate the burden of mental disorders in low-and
middle-income-countries through identification of new mechanistic pathways which can lead …

“When I woke up I was so worried and ashamed, I thought it was a disease”: Adolescent boys' transitions through puberty in Kenya

A Carney, T Mulei, D Kurao, C Hagstrom… - … in Reproductive Health, 2022 - frontiersin.org
Growing evidence suggests a need for more focused attention on boys' experiences of
puberty in sub-Saharan Africa to assure healthy transitions into young adulthood. Existing …

Physical Activity and Its Association With Body Mass Index: A Cross-Sectional Analysis in Middle-Aged Adults From 4 Sub-Saharan African Countries

M Muti, LJ Ware, LK Micklesfield… - … of Physical Activity …, 2023 - journals.humankinetics.com
Background: This study aimed to explore association of self-reported physical activity
domains of work, leisure, and transport-related physical activity and body mass index (BMI) …

Variability of polygenic prediction for body mass index in Africa

T Chikowore, K Läll, LK Micklesfield, Z Lombard… - Genome Medicine, 2024 - Springer
Background Polygenic prediction studies in continental Africans are scarce. Africa's genetic
and environmental diversity pose a challenge that limits the generalizability of polygenic risk …

The Effects of COVID-19 Pandemic Lockdowns on Alcohol Consumption and Tobacco Smoking Behaviour in South Africa: A National Survey

W Mapanga, A Craig, A Mtintsilana… - European addiction …, 2023 - karger.com
Introduction: During the first phase of the coronavirus (COVID-19) pandemic lockdowns in
South Africa (SA), both alcohol and tobacco were considered non-essential goods and their …