Mammalian stress granules and P bodies at a glance
Stress granules (SGs) and processing bodies (PBs) are membraneless ribonucleoprotein-
based cellular compartments that assemble in response to stress. SGs and PBs form …
based cellular compartments that assemble in response to stress. SGs and PBs form …
[HTML][HTML] Molecular mechanisms of stress granule assembly and disassembly
S Hofmann, N Kedersha, P Anderson… - Biochimica et Biophysica …, 2021 - Elsevier
Stress granules (SGs) are membrane-less ribonucleoprotein (RNP)-based cellular
compartments that form in the cytoplasm of a cell upon exposure to various environmental …
compartments that form in the cytoplasm of a cell upon exposure to various environmental …
Friend or foe—Post-translational modifications as regulators of phase separation and RNP granule dynamics
M Hofweber, D Dormann - Journal of Biological Chemistry, 2019 - ASBMB
Ribonucleoprotein (RNP) granules are membrane-less organelles consisting of RNA-
binding proteins (RBPs) and RNA. RNA granules form through liquid–liquid phase …
binding proteins (RBPs) and RNA. RNA granules form through liquid–liquid phase …
[HTML][HTML] Who's in and who's out—compositional control of biomolecular condensates
Biomolecular condensates are two-and three-dimensional compartments in eukaryotic cells
that concentrate specific collections of molecules without an encapsulating membrane …
that concentrate specific collections of molecules without an encapsulating membrane …
A new phase of networking: the molecular composition and regulatory dynamics of mammalian stress granules
SR Millar, JQ Huang, KJ Schreiber, YC Tsai… - Chemical …, 2023 - ACS Publications
Stress granules (SGs) are cytosolic biomolecular condensates that form in response to
cellular stress. Weak, multivalent interactions between their protein and RNA constituents …
cellular stress. Weak, multivalent interactions between their protein and RNA constituents …
Ubiquitin modulates liquid-liquid phase separation of UBQLN2 via disruption of multivalent interactions
TP Dao, RM Kolaitis, HJ Kim, K O'Donovan… - Molecular cell, 2018 - cell.com
Under stress, certain eukaryotic proteins and RNA assemble to form membraneless
organelles known as stress granules. The most well-studied stress granule components are …
organelles known as stress granules. The most well-studied stress granule components are …
Translation inhibition and stress granules in the antiviral immune response
C McCormick, DA Khaperskyy - Nature Reviews Immunology, 2017 - nature.com
Efficient viral gene expression is threatened by cellular stress response programmes that
rapidly reprioritize the translation machinery in response to varied environmental assaults …
rapidly reprioritize the translation machinery in response to varied environmental assaults …
Stress‐induced mRNP granules: Form and function of processing bodies and stress granules
In response to stress, cells must quickly reprogram gene expression to adapt and survive.
This is achieved in part by altering levels of mRNAs and their translation into proteins …
This is achieved in part by altering levels of mRNAs and their translation into proteins …
Dance with the devil: stress granules and signaling in antiviral responses
N Eiermann, K Haneke, Z Sun, G Stoecklin, A Ruggieri - Viruses, 2020 - mdpi.com
Cells have evolved highly specialized sentinels that detect viral infection and elicit an
antiviral response. Among these, the stress-sensing protein kinase R, which is activated by …
antiviral response. Among these, the stress-sensing protein kinase R, which is activated by …
Stress granule formation, disassembly, and composition are regulated by alphavirus ADP-ribosylhydrolase activity
AK Jayabalan, S Adivarahan… - Proceedings of the …, 2021 - National Acad Sciences
While biomolecular condensates have emerged as an important biological phenomenon,
mechanisms regulating their composition and the ways that viruses hijack these …
mechanisms regulating their composition and the ways that viruses hijack these …