ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: part 1 of 2—evidence base …

S Dorbala, Y Ando, S Bokhari… - Circulation …, 2021 - Am Heart Assoc
Sharmila Dorbala, MD, MPH, FASNC, Chair*; Yukio Ando, MD, PhD†; Sabahat Bokhari,
MD‡; Angela Dispenzieri, MD § ; Rodney H. Falk, MD*; Victor A. Ferrari, MD∥; Marianna …

Cardiac Scintigraphy With Technetium-99m-Labeled Bone-Seeking Tracers for Suspected Amyloidosis: JACC Review Topic of the Week

M Hanna, FL Ruberg, MS Maurer, A Dispenzieri… - Journal of the American …, 2020 - jacc.org
Technetium-labeled cardiac scintigraphy (ie, Tc-PYP scan) has been repurposed for the
diagnosis of transthyretin amyloid cardiomyopathy (ATTR-CM). Validated in cohorts of …

JCS 2020 guideline on diagnosis and treatment of cardiac amyloidosis

H Kitaoka, C Izumi, Y Izumiya, T Inomata, M Ueda… - Circulation …, 2020 - jstage.jst.go.jp
[CQ1] What is the role of 99 mTc-PYP scintigraphy (bone scintigraphy) in clinical practice for
CA?∙∙∙∙∙∙ 1655 [CQ2] The role of endomyocardial biopsy. Which site is appropriate for biopsy …

Low sensitivity of bone scintigraphy in detecting Phe64Leu mutation-related transthyretin cardiac amyloidosis

MB Musumeci, F Cappelli, D Russo, G Tini… - Cardiovascular …, 2020 - jacc.org
Objectives The aim of this study was to assess the diagnostic accuracy of bone scintigraphy
in a large multicenter cohort of patients with cardiac amyloidotic involvement and Phe64Leu …

Diagnostic performance of imaging investigations in detecting and differentiating cardiac amyloidosis: a systematic review and meta‐analysis

J Brownrigg, M Lorenzini, M Lumley… - ESC heart failure, 2019 - Wiley Online Library
Aims The study aims to systematically assess the diagnostic performance of cardiac
magnetic resonance (CMR) and nuclear scintigraphy (index tests) for the diagnosis and …

Diagnostic accuracy of bone scintigraphy in the assessment of cardiac transthyretin-related amyloidosis: a bivariate meta-analysis

G Treglia, AWJM Glaudemans, F Bertagna… - European journal of …, 2018 - Springer
Purpose Cardiac transthyretin-related amyloidosis (ATTR) is a progressive and fatal
cardiomyopathy. The diagnosis of this disease is frequently delayed or missed due to the …

The impact of patients with cardiac amyloidosis in HFpEF trials

S Oghina, W Bougouin, M Bézard, M Kharoubi… - Heart Failure, 2021 - jacc.org
Heart failure with preserved ejection fraction (HFpEF) is an increasingly diagnosed condition
whose failure to respond to new drugs effective in heart failure with reduced ejection fraction …

Keys to early diagnosis of cardiac amyloidosis: red flags from clinical, laboratory and imaging findings

G Vergaro, A Aimo, A Barison… - European journal of …, 2020 - journals.sagepub.com
Cardiac involvement in systemic amyloidosis, due either to immunoglobulin light-chain or
transthyretin amyloidosis, influences clinical presentation and is a strong predictor of …

Prevalence of wild type ATTR assessed as myocardial uptake in bone scan in the elderly population

L Mohamed-Salem, JJ Santos-Mateo… - International journal of …, 2018 - Elsevier
Background Myocardial uptake of bone tracers has emerged as useful tool for the early
detection of transthyretin amyloidosis (ATTR). The prevalence of wild-type ATTR (ATTRwt) in …

Current and evolving multimodality cardiac imaging in managing transthyretin amyloid cardiomyopathy

L Alwan, DC Benz, SAM Cuddy, S Dobner, I Shiri… - Cardiovascular …, 2024 - jacc.org
Amyloid transthyretin (ATTR) amyloidosis is a protein-misfolding disease characterized by
fibril accumulation in the extracellular space that can result in local tissue disruption and …