Developmental neurotoxicity testing: a path forward
KM Crofton, WR Mundy, TJ Shafer - Congenital anomalies, 2012 - Wiley Online Library
Great progress has been made over the past 40 years in understanding the hazards of
exposure to a small number of developmental neurotoxicants. Lead, polychlorinated …
exposure to a small number of developmental neurotoxicants. Lead, polychlorinated …
Coaxial electrospun poly (lactic acid)/silk fibroin nanofibers incorporated with nerve growth factor support the differentiation of neuronal stem cells
Coaxial electrospinning is an explicit method for encapsulation of protein drugs, and the
process could preserve the bioactivity of the molecules. In this study, coaxial electrospinning …
process could preserve the bioactivity of the molecules. In this study, coaxial electrospinning …
[HTML][HTML] Innervation of cervical carcinoma is mediated by cancer-derived exosomes
CT Lucido, E Wynja, M Madeo, CS Williamson… - Gynecologic …, 2019 - Elsevier
Objective Recently, our laboratory identified sensory innervation within head and neck
squamous cell carcinomas (HNSCCs) and subsequently defined a mechanism whereby …
squamous cell carcinomas (HNSCCs) and subsequently defined a mechanism whereby …
[HTML][HTML] A high-throughput approach to identify specific neurotoxicants/developmental toxicants in human neuronal cell function assays
J Delp, S Gutbier, S Klima, L Hoelting, K Pinto-Gil… - Altex, 2018 - ncbi.nlm.nih.gov
The (developmental) neurotoxicity hazard is still unknown for most chemicals. Establishing a
test battery covering most of the relevant adverse outcome pathways may close this gap …
test battery covering most of the relevant adverse outcome pathways may close this gap …
Cooperative effect of heparan sulfate and laminin mimetic peptide nanofibers on the promotion of neurite outgrowth
Extracellular matrix contains an abundant variety of signals that are received by cell surface
receptors contributing to cell fate, via regulation of cellular activities such as proliferation …
receptors contributing to cell fate, via regulation of cellular activities such as proliferation …
Biocompatible electroactive tetra (aniline)-conjugated peptide nanofibers for neural differentiation
Peripheral nerve injuries cause devastating problems for the quality of patients' lives, and
regeneration following damage to the peripheral nervous system is limited depending on the …
regeneration following damage to the peripheral nervous system is limited depending on the …
Nerve growth factor induces neurite outgrowth of PC12 cells by promoting Gβγ-microtubule interaction
JA Sierra-Fonseca, O Najera, J Martinez-Jurado… - BMC neuroscience, 2014 - Springer
Background Assembly and disassembly of microtubules (MTs) is critical for neurite
outgrowth and differentiation. Evidence suggests that nerve growth factor (NGF) induces …
outgrowth and differentiation. Evidence suggests that nerve growth factor (NGF) induces …
Multiparametric High Content Analysis for assessment of neurotoxicity in differentiated neuronal cell lines and human embryonic stem cell-derived neurons
MS Wilson, JR Graham, AJ Ball - Neurotoxicology, 2014 - Elsevier
The potential for adverse neurotoxic reactions in response to therapeutics and
environmental hazards continues to prompt development of novel cell-based assays to …
environmental hazards continues to prompt development of novel cell-based assays to …
The Effect of Psoralea corylifolia (Babchi) on Neuronal Apoptosis Induced by Palmitate in PC12 Cells and its Role in Alzheimer's Disease: A Review
S Ranjan, NS Kushwaha, S Trivedi… - Pharmacognosy …, 2024 - journals.sagepub.com
Background: Psoralea corylifolia (PC) seed extract (PCE) has been extensively utilized as
an herbal drug due to its favorable effects on human health. It's extracts and active …
an herbal drug due to its favorable effects on human health. It's extracts and active …
Thermal-corrosion-free electrode-integrated cell chip for promotion of electrically stimulated neurite outgrowth
SM Lee, JE Lee, YK Lee, DA Yoo, DB Seon, DW Lee… - BioChip Journal, 2022 - Springer
In neural tissue engineering, the use of electrical stimulation has been proposed to cure
patients with damaged nervous systems. Electrical stimulation can promote nerve cell …
patients with damaged nervous systems. Electrical stimulation can promote nerve cell …