Developmental neurotoxicity testing: a path forward

KM Crofton, WR Mundy, TJ Shafer - Congenital anomalies, 2012 - Wiley Online Library
Great progress has been made over the past 40 years in understanding the hazards of
exposure to a small number of developmental neurotoxicants. Lead, polychlorinated …

Coaxial electrospun poly (lactic acid)/silk fibroin nanofibers incorporated with nerve growth factor support the differentiation of neuronal stem cells

L Tian, MP Prabhakaran, J Hu, M Chen… - RSC Advances, 2015 - pubs.rsc.org
Coaxial electrospinning is an explicit method for encapsulation of protein drugs, and the
process could preserve the bioactivity of the molecules. In this study, coaxial electrospinning …

[HTML][HTML] Innervation of cervical carcinoma is mediated by cancer-derived exosomes

CT Lucido, E Wynja, M Madeo, CS Williamson… - Gynecologic …, 2019 - Elsevier
Objective Recently, our laboratory identified sensory innervation within head and neck
squamous cell carcinomas (HNSCCs) and subsequently defined a mechanism whereby …

[HTML][HTML] A high-throughput approach to identify specific neurotoxicants/developmental toxicants in human neuronal cell function assays

J Delp, S Gutbier, S Klima, L Hoelting, K Pinto-Gil… - Altex, 2018 - ncbi.nlm.nih.gov
The (developmental) neurotoxicity hazard is still unknown for most chemicals. Establishing a
test battery covering most of the relevant adverse outcome pathways may close this gap …

Cooperative effect of heparan sulfate and laminin mimetic peptide nanofibers on the promotion of neurite outgrowth

B Mammadov, R Mammadov, MO Guler, AB Tekinay - Acta biomaterialia, 2012 - Elsevier
Extracellular matrix contains an abundant variety of signals that are received by cell surface
receptors contributing to cell fate, via regulation of cellular activities such as proliferation …

Biocompatible electroactive tetra (aniline)-conjugated peptide nanofibers for neural differentiation

I Arioz, O Erol, G Bakan, FB Dikecoglu… - … applied materials & …, 2018 - ACS Publications
Peripheral nerve injuries cause devastating problems for the quality of patients' lives, and
regeneration following damage to the peripheral nervous system is limited depending on the …

Nerve growth factor induces neurite outgrowth of PC12 cells by promoting Gβγ-microtubule interaction

JA Sierra-Fonseca, O Najera, J Martinez-Jurado… - BMC neuroscience, 2014 - Springer
Background Assembly and disassembly of microtubules (MTs) is critical for neurite
outgrowth and differentiation. Evidence suggests that nerve growth factor (NGF) induces …

Multiparametric High Content Analysis for assessment of neurotoxicity in differentiated neuronal cell lines and human embryonic stem cell-derived neurons

MS Wilson, JR Graham, AJ Ball - Neurotoxicology, 2014 - Elsevier
The potential for adverse neurotoxic reactions in response to therapeutics and
environmental hazards continues to prompt development of novel cell-based assays to …

The Effect of Psoralea corylifolia (Babchi) on Neuronal Apoptosis Induced by Palmitate in PC12 Cells and its Role in Alzheimer's Disease: A Review

S Ranjan, NS Kushwaha, S Trivedi… - Pharmacognosy …, 2024 - journals.sagepub.com
Background: Psoralea corylifolia (PC) seed extract (PCE) has been extensively utilized as
an herbal drug due to its favorable effects on human health. It's extracts and active …

Thermal-corrosion-free electrode-integrated cell chip for promotion of electrically stimulated neurite outgrowth

SM Lee, JE Lee, YK Lee, DA Yoo, DB Seon, DW Lee… - BioChip Journal, 2022 - Springer
In neural tissue engineering, the use of electrical stimulation has been proposed to cure
patients with damaged nervous systems. Electrical stimulation can promote nerve cell …