Background: Cancer is a disease characterized by uncontrolled cell growth and
proliferation. It has become a major health problem in the past decades and is now the …

Throughout history, natural products have afforded a rich source of compounds that have
found many applications in the fields of medicine, pharmacy and biology. Within the sphere …

Eukaryotic elongation factor 2 kinase (eEF2K) is a member of the small group of atypical 'α-
kinases'. It phosphorylates and inhibits eukaryotic elongation factor 2, to slow down the …

Recent studies have shown that cancer immunotherapy could be a promising therapeutic
approach for the treatment of cancer. In the present study, to identify novel tumor-associated …

Doxorubicin (DOX) is involved in the induction of DNA damage, inhibition of cell
proliferation, impairment of mitochondria, and cell death. To determine the biological effects …

The alpha-kinase family represents a class of atypical protein kinases that display little
sequence similarity to conventional protein kinases. Early studies on myosin heavy chain …

Cell cycling and protein synthesis are both key physiological tasks for cancer cells. Here we
present a model for how the elongation phase of protein synthesis, governed by elongation …

This review surveys the diversity of natural products (NPs) derived from terrestrial plants,
micro-organisms, marine organisms and fungi used in the treatment of various diseases. A …

Background Dihydroartemisinin (DHA), a semi-synthetic derivative of artemisinin, has
recently shown antitumor activity in various cancer cells. Apo2 ligand or tumor necrosis …

Doxorubicin (DOX) is an anthracycline antibiotic that is widely used to treat different types of
malignancy. In this study, it was studied whether DOX could be used to render tumor cells …