Antisense RNAs encoded on the DNA strand opposite another gene have the potential to
form extensive base-pairing interactions with the corresponding sense RNA. Unlike other …

Bacteria constitute a large and diverse class of infectious agents, causing devastating
diseases in humans, animals, and plants. Our understanding of gene expression control …

For decades, identifying the regions of a bacterial chromosome that are necessary for
viability has relied on mapping integration sites in libraries of random transposon mutants to …

TubercuList (http://tuberculist. epfl. ch/), the relational database that presents genome-
derived information about H37Rv, the paradigm strain of Mycobacterium tuberculosis, has …

Abstract Background Structured noncoding RNAs perform many functions that are essential
for protein synthesis, RNA processing, and gene regulation. Structured RNAs can be …

Identifying genomic elements required for viability is central to our understanding of the
basic physiology of bacterial pathogens. Recently, the combination of high-density …

RNA sequencing provides a new perspective on the genome of Mycobacterium tuberculosis
by revealing an extensive presence of non-coding RNA, including long 5'and 3'untranslated …

Renewed efforts in tuberculosis (TB) research have led to important new insights into the
biology and epidemiology of this devastating disease. Yet, in the face of the modern …

In recent years, non-coding RNAs have emerged as key regulators of gene expression.
Among these RNAs, the antisense RNAs (asRNAs) are particularly abundant, but in most …

Bacteria are often exposed to a hostile environment and have developed a plethora of
cellular processes in order to survive. A burgeoning list of small non-coding RNAs (sRNAs) …