Endothelial barrier function and leukocyte transmigration in atherosclerosis
The vascular endothelium is a highly specialized barrier that controls passage of fluids and
migration of cells from the lumen into the vessel wall. Endothelial cells assist leukocytes to …
migration of cells from the lumen into the vessel wall. Endothelial cells assist leukocytes to …
Extracellular matrix remodeling in vascular disease: defining its regulators and pathological influence
PK Lin, GE Davis - Arteriosclerosis, Thrombosis, and Vascular …, 2023 - Am Heart Assoc
Because of structural and cellular differences (ie, degrees of matrix abundance and cross-
linking, mural cell density, and adventitia), large and medium-sized vessels, in comparison …
linking, mural cell density, and adventitia), large and medium-sized vessels, in comparison …
The role of hepcidin and iron homeostasis in atherosclerosis
F Wunderer, L Traeger, HH Sigurslid… - Pharmacological …, 2020 - Elsevier
Atherosclerotic cardiovascular disease is a major burden on global health and a leading
cause of death worldwide. The pathophysiology of this chronic disease is complex, involving …
cause of death worldwide. The pathophysiology of this chronic disease is complex, involving …
Inflammation in vein graft disease
MR De Vries, PHA Quax - Frontiers in cardiovascular medicine, 2018 - frontiersin.org
Bypass surgery is one of the most frequently used strategies to revascularize tissues
downstream occlusive atherosclerotic lesions. For venous bypass surgery the great …
downstream occlusive atherosclerotic lesions. For venous bypass surgery the great …
T cell co-stimulation and co-inhibition in cardiovascular disease: a double-edged sword
KH Simons, A de Jong, JW Jukema… - Nature Reviews …, 2019 - nature.com
The role of inflammation in cardiovascular disease (CVD) is now widely accepted. Immune
cells, including T cells, are influenced by inflammatory signals and contribute to the onset …
cells, including T cells, are influenced by inflammatory signals and contribute to the onset …
Hypoxia-inducible factor-1α: the master regulator of endothelial cell senescence in vascular aging
Aging is one of the hottest topics in biomedical research. Advances in research and
medicine have helped to preserve human health, leading to an extension of life expectancy …
medicine have helped to preserve human health, leading to an extension of life expectancy …
Mitophagy in atherosclerosis: from mechanism to therapy
Y Zhang, J Weng, L Huan, S Sheng, F Xu - Frontiers in Immunology, 2023 - frontiersin.org
Mitophagy is a type of autophagy that can selectively eliminate damaged and depolarized
mitochondria to maintain mitochondrial activity and cellular homeostasis. Several pathways …
mitochondria to maintain mitochondrial activity and cellular homeostasis. Several pathways …
[HTML][HTML] Plaque elasticity and intraplaque neovascularisation on carotid artery ultrasound: a comparative histological study
Y Zhang, J Cao, J Zhou, C Zhang, Q Li, S Chen… - European Journal of …, 2021 - Elsevier
Objective Plaque elasticity and intraplaque neovascularisation are strongly suggestive of
vulnerable plaque. This study aimed to investigate the relationship between intraplaque …
vulnerable plaque. This study aimed to investigate the relationship between intraplaque …
Optical/MRI dual-modality imaging of M1 macrophage polarization in atherosclerotic plaque with MARCO-targeted upconversion luminescence probe
Y Wang, Y Zhang, Z Wang, J Zhang, RR Qiao, M Xu… - Biomaterials, 2019 - Elsevier
Pro-inflammatory M1 macrophage is identified as a prominent component initializing the
progress of vulnerable atherosclerotic plaque. Here, we constructed anti-MARCO NaGdF 4 …
progress of vulnerable atherosclerotic plaque. Here, we constructed anti-MARCO NaGdF 4 …
One Endothelium-Targeted Combined Nucleic Acid Delivery System for Myocardial Infarction Therapy
Y Shao, C Xu, S Zhu, J Wu, C Sun, S Huang, G Li… - ACS …, 2024 - ACS Publications
Acute myocardial infarction (MI) and ischemic heart disease are the leading causes of heart
failure and mortality. Currently, research on MI treatment is focused on angiogenic and anti …
failure and mortality. Currently, research on MI treatment is focused on angiogenic and anti …