Mechanisms of antifungal drug resistance
LE Cowen, D Sanglard… - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Antifungal therapy is a central component of patient management for acute and chronic
mycoses. Yet, treatment choices are restricted because of the sparse number of antifungal …
mycoses. Yet, treatment choices are restricted because of the sparse number of antifungal …
Candida and Candidiasis—Opportunism Versus Pathogenicity: A Review of the Virulence Traits
One of the most important questions in microbiology nowadays, is how apparently harmless,
commensal yeasts like Candida spp. can cause a rising number of infections. The …
commensal yeasts like Candida spp. can cause a rising number of infections. The …
A Candida albicans CRISPR system permits genetic engineering of essential genes and gene families
VK Vyas, MI Barrasa, GR Fink - Science advances, 2015 - science.org
Candida albicans is a pathogenic yeast that causes mucosal and systematic infections with
high mortality. The absence of facile molecular genetics has been a major impediment to …
high mortality. The absence of facile molecular genetics has been a major impediment to …
Candida albicans, a major human fungal pathogen
Candida albicans is the most common human fungal pathogen (Beck-Sague and Jarvis,
1993). It is normally a harmless commensal organism. However, it is a opportunistic …
1993). It is normally a harmless commensal organism. However, it is a opportunistic …
Evolution of pathogenicity and sexual reproduction in eight Candida genomes
Candida species are the most common cause of opportunistic fungal infection worldwide.
Here we report the genome sequences of six Candida species and compare these and …
Here we report the genome sequences of six Candida species and compare these and …
The Candida Genome Database (CGD): incorporation of Assembly 22, systematic identifiers and visualization of high throughput sequencing data
MS Skrzypek, J Binkley, G Binkley… - Nucleic acids …, 2016 - academic.oup.com
Abstract The Candida Genome Database (CGD, http://www. candidagenome. org/) is a
freely available online resource that provides gene, protein and sequence information for …
freely available online resource that provides gene, protein and sequence information for …
The Candida pathogenic species complex
Candida species are the most common causes of fungal infection. Approximately 90% of
infections are caused by five species: Candida albicans, Candida glabrata, Candida …
infections are caused by five species: Candida albicans, Candida glabrata, Candida …
Efflux-mediated antifungal drug resistance
Fungi cause serious infections in the immunocompromised and debilitated, and the
incidence of invasive mycoses has increased significantly over the last 3 decades. Slow …
incidence of invasive mycoses has increased significantly over the last 3 decades. Slow …
Candida albicans Cell Wall Proteins
WLJ Chaffin - Microbiology and molecular biology reviews, 2008 - Am Soc Microbiol
The Candida albicans cell wall maintains the structural integrity of the organism in addtion to
providing a physical contact interface with the environment. The major components of the …
providing a physical contact interface with the environment. The major components of the …
A Phenotypic Profile of the Candida albicans Regulatory Network
OR Homann, J Dea, SM Noble, AD Johnson - PLoS genetics, 2009 - journals.plos.org
Candida albicans is a normal resident of the gastrointestinal tract and also the most
prevalent fungal pathogen of humans. It last shared a common ancestor with the model …
prevalent fungal pathogen of humans. It last shared a common ancestor with the model …