Murine models of colorectal cancer: the azoxymethane (AOM)/dextran sulfate sodium (DSS) model of colitis-associated cancer

D Dzhalilova, N Zolotova, N Fokichev, O Makarova - PeerJ, 2023 - peerj.com
Background Colorectal cancer (CRC) is the third most common cancer. It is a
heterogeneous disease, including both hereditary and sporadic types of tumors. CRC …

Platelet status in cancer cachexia progression in ApcMin/+ mice

P Cunningham, CA Unger, EA Patton, A Aiken… - Frontiers in …, 2023 - frontiersin.org
Cachexia, a complex wasting syndrome, significantly affects the quality of life and treatment
options for cancer patients. Studies have reported a strong correlation between high platelet …

Acute administration of ojeok-san ameliorates pain-like behaviors in pre-clinical models of inflammatory bowel diseases

EA Patton, P Cunningham, M Noneman, HP Helms… - Nutrients, 2023 - mdpi.com
(1) Background: Gastrointestinal pain and fatigue are the most reported concerns of patients
with inflammatory bowel disease (IBD). Commonly prescribed drugs focus on decreasing …

Ojeok-san enhances platinum sensitivity in ovarian cancer by regulating adipocyte paracrine IGF1 secretion

J Ma, J Li, X Chen, Y Ma - Adipocyte, 2024 - Taylor & Francis
Background Platinum is a commonly used drug for ovarian cancer (OvCa) treatment, but
drug resistance limits its clinical application. This study intended to delineate the effects of …

Ultra-high performance liquid chromatography-tandem mass spectrometry assay for simultaneous determination of 22 marker compounds in traditional herbal …

HS Kim, SH Baek - Journal of Pharmaceutical and Biomedical Analysis, 2024 - Elsevier
Traditional herbal medicines (THMs) have long been in use worldwide and are considered
safe for use as tonics or complementary treatments for many diseases. Advanced quality …

Ojeoksan Ameliorates Cisplatin-Induced Acute Kidney Injury in Mice by Downregulating MAPK and NF-κB Pathways

DU Kim, B Kweon, JY Oh, CS Seo, DG Kim… - International Journal of …, 2022 - mdpi.com
Acute kidney injury (AKI) is a major side effect of cisplatin, a crucial anticancer agent.
Therefore, it is necessary to develop drugs to protect against cisplatin-induced …