Stem cell therapy in heart diseases–cell types, mechanisms and improvement strategies
P Müller, H Lemcke, R David - Cellular Physiology and Biochemistry, 2018 - karger.com
A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …
approach for the treatment of cardiovascular diseases. Since the first transplantation into …
Cell therapy trials for heart regeneration—lessons learned and future directions
P Menasché - Nature Reviews Cardiology, 2018 - nature.com
The effects of cell therapy on heart regeneration in patients with chronic cardiomyopathy
have been assessed in several clinical trials. These trials can be categorized as those using …
have been assessed in several clinical trials. These trials can be categorized as those using …
Stem cell therapy for chronic ischaemic heart disease and congestive heart failure
Background A promising approach to the treatment of chronic ischaemic heart disease and
congestive heart failure is the use of stem cells. The last decade has seen a plethora of …
congestive heart failure is the use of stem cells. The last decade has seen a plethora of …
Synthetic mRNA encoding VEGF-A in patients undergoing coronary artery bypass grafting: design of a phase 2a clinical trial
V Anttila, A Saraste, J Knuuti, P Jaakkola… - … therapy Methods & …, 2020 - cell.com
Therapeutic angiogenesis may improve outcomes in patients with coronary artery disease
undergoing surgical revascularization. Angiogenic factors may promote blood vessel growth …
undergoing surgical revascularization. Angiogenic factors may promote blood vessel growth …
Meta-analysis of cell therapy trials for patients with heart failure
Rationale: Cell-based therapies are a promising intervention for the treatment of heart failure
(HF) secondary to ischemic and nonischemic cardiomyopathy. However, the clinical efficacy …
(HF) secondary to ischemic and nonischemic cardiomyopathy. However, the clinical efficacy …
Design of injectable materials to improve stem cell transplantation
LM Marquardt, SC Heilshorn - Current stem cell reports, 2016 - Springer
Stem cell-based therapies are steadily gaining traction for regenerative medicine
approaches to treating disease and injury throughout the body. While a significant body of …
approaches to treating disease and injury throughout the body. While a significant body of …
Adult stem cells for regenerative therapy
Cell therapy has been identified as an effective method to regenerate damaged tissue. Adult
stem cells, also known as somatic stem cells or resident stem cells, are a rare population of …
stem cells, also known as somatic stem cells or resident stem cells, are a rare population of …
Translational cardiac stem cell therapy: advancing from first-generation to next-generation cell types
E Cambria, FS Pasqualini, P Wolint, J Günter… - NPJ Regenerative …, 2017 - nature.com
Acute myocardial infarction and chronic heart failure rank among the major causes of
morbidity and mortality worldwide. Except for heart transplantation, current therapy options …
morbidity and mortality worldwide. Except for heart transplantation, current therapy options …
Global position paper on cardiovascular regenerative medicine
F Fernández-Avilés, R Sanz-Ruiz… - European heart …, 2017 - academic.oup.com
Based on the increasingly understood regenerative capacity of the human heart and
vascular system, 1 cardiovascular regenerative medicine (CRM) encompasses all potential …
vascular system, 1 cardiovascular regenerative medicine (CRM) encompasses all potential …
Approaches to therapeutic angiogenesis for ischemic heart disease
T Johnson, L Zhao, G Manuel, H Taylor… - Journal of Molecular …, 2019 - Springer
Ischemic heart disease (IHD) is caused by the narrowing of arteries that work to provide
blood, nutrients, and oxygen to the myocardial tissue. The worldwide epidemic of IHD …
blood, nutrients, and oxygen to the myocardial tissue. The worldwide epidemic of IHD …