Compound–protein interaction prediction by deep learning: databases, descriptors and models

BX Du, Y Qin, YF Jiang, Y Xu, SM Yiu, H Yu, JY Shi - Drug discovery today, 2022 - Elsevier
The screening of compound–protein interactions (CPIs) is one of the most crucial steps in
finding hit and lead compounds. Deep learning (DL) methods for CPI prediction can address …

What Makes GPCRs from Different Families Bind to the Same Ligand?

KO Dankwah, JE Mohl, K Begum, MY Leung - Biomolecules, 2022 - mdpi.com
G protein-coupled receptors (GPCRs) are the largest class of cell-surface receptor proteins
with important functions in signal transduction and often serve as therapeutic drug targets …

Integration of 3D Structural and Sequence Features to Predict GPCR Ligand Binding

KO Dankwah - 2020 - search.proquest.com
G protein-coupled receptors (GPCRs) are the largest class of cell-surface receptor proteins
with important functions in signal transduction and often serve as therapeutic drug targets …