Marine natural products
Covering: 2014. Previous review: Nat. Prod. Rep., 2015, 32, 116–211 This review covers the
literature published in 2014 for marine natural products (MNPs), with 1116 citations (753 for …
literature published in 2014 for marine natural products (MNPs), with 1116 citations (753 for …
Chalcone derivatives and their antibacterial activities: Current development
M Xu, P Wu, F Shen, J Ji, KP Rakesh - Bioorganic Chemistry, 2019 - Elsevier
The increase in antibiotic resistance due to various factors has encouraged the look for
novel compounds which are active against multidrug-resistant pathogens. In this framework …
novel compounds which are active against multidrug-resistant pathogens. In this framework …
Tackling antibiotic resistance with compounds of natural origin: A comprehensive review
Drug-resistant bacteria pose a serious threat to human health worldwide. Current antibiotics
are losing efficacy and new antimicrobial agents are urgently needed. Living organisms are …
are losing efficacy and new antimicrobial agents are urgently needed. Living organisms are …
Siderophores in iron metabolism: from mechanism to therapy potential
BR Wilson, AR Bogdan, M Miyazawa… - Trends in molecular …, 2016 - cell.com
Iron is an essential nutrient for life. During infection, a fierce battle of iron acquisition occurs
between the host and bacterial pathogens. Bacteria acquire iron by secreting siderophores …
between the host and bacterial pathogens. Bacteria acquire iron by secreting siderophores …
Staphylococcus aureus pathogenesis in diverse host environments
D Balasubramanian, L Harper, B Shopsin… - Pathogens and …, 2017 - academic.oup.com
Staphylococcus aureus is an eminent human pathogen that can colonize the human host
and cause severe life-threatening illnesses. This bacterium can reside in and infect a wide …
and cause severe life-threatening illnesses. This bacterium can reside in and infect a wide …
Natural products as a source for novel antibiotics
MG Moloney - Trends in pharmacological sciences, 2016 - cell.com
Natural products have historically been of crucial importance in the identification and
development of antibacterial agents. Interest in these systems has waned in recent years …
development of antibacterial agents. Interest in these systems has waned in recent years …
Something old, something new: revisiting natural products in antibiotic drug discovery
GD Wright - Canadian journal of microbiology, 2014 - cdnsciencepub.com
Antibiotic discovery is in crisis. Despite a growing need for new drugs resulting from the
increasing number of multi-antibiotic-resistant pathogens, there have been only a handful of …
increasing number of multi-antibiotic-resistant pathogens, there have been only a handful of …
Pitfalls in the structural elucidation of small molecules. A critical analysis of a decade of structural misassignments of marine natural products
SM Shen, G Appendino, YW Guo - Natural Product Reports, 2022 - pubs.rsc.org
Covering: July 2010 to August 2021 This article summarizes more than 200 cases of
misassigned marine natural products reported between July 2010 and August 2021, sorting …
misassigned marine natural products reported between July 2010 and August 2021, sorting …
Creating and screening natural product libraries
BAP Wilson, CC Thornburg, CJ Henrich… - Natural product …, 2020 - pubs.rsc.org
Covering: up to 2020 The National Cancer Institute of the United States (NCI) has initiated a
Cancer Moonshot program entitled the NCI Program for Natural Product Discovery. As part …
Cancer Moonshot program entitled the NCI Program for Natural Product Discovery. As part …
Recent developments in understanding the iron acquisition strategies of gram positive pathogens
JR Sheldon, DE Heinrichs - FEMS microbiology reviews, 2015 - academic.oup.com
Iron is a versatile redox-active catalyst and a required cofactor within a diverse array of
biological processes. To almost all organisms, iron is both essential and potentially toxic …
biological processes. To almost all organisms, iron is both essential and potentially toxic …