To facilitate the process of aging healthily and prevent age-related health problems, efforts
to properly understand aging mechanisms and develop effective and affordable anti-aging …

Present review article highlights various cardiovascular risk prediction biomarkers by
incorporating both traditional risk factors to be used as diagnostic markers and recent …

Osteoblast apoptosis plays an important role in age-related bone loss and osteoporosis. Our
previous study revealed that advanced oxidation protein products (AOPPs) could induce …

Mid-life stage adults are at higher risk of developing venous thrombosis
(VT)/thromboembolism (VT/E). Aging is characterized by an overproduction of reactive …

Dietary methionine restriction (MR) has been shown to delay aging and ameliorate age-
related cognitive impairments. We hypothesized that changes in the gut microbiota may …

Astaxanthin (AX) is a red-colored xanthophyll carotenoid with potent antioxidant, anti-
inflammatory, and neuroprotective properties. However, the underlying in vivo mechanism …

Objective. This study evaluated oxidative damage caused to the salivary glands in
streptozotocin‐induced diabetes (DM). Materials and Methods. Rats were divided into 4 …

We aimed to investigate the effect of chronic D-galactose exposure on the mimicking of
natural aging processes based upon the hallmarks of aging. Seven-week-old male Wistar …

d-Galactose (d-Gal), when abnormally accumulated in the plasma, results in oxidative stress
production, and may alter the homeostasis of erythrocytes, which are particularly exposed to …

Metformin, a biguanide drug commonly used to treat type 2 diabetes, has been noted to
function as a caloric restriction mimetic. Its antidiabetic effect notwithstanding, metformin is …