SUMMARY A major part of organismal complexity and versatility of prokaryotes resides in
their ability to fine-tune gene expression to adequately respond to internal and external …

Genomics has set the basis for a variety of methodologies that produce high-throughput
datasets identifying the different players that define gene regulation, particularly regulation …

Abstract RSAT (Regulatory Sequence Analysis Tools) enables the detection and the
analysis of cis-regulatory elements in genomic sequences. This software suite performs (i) …

Phosphate limitation is important for production of antibiotics and other secondary
metabolites in Streptomyces. Phosphate control is mediated by the two-component system …

The mechanisms by which the p53 tumor suppressor acts remain incompletely understood.
To gain new insights into p53 biology, we used high-throughput sequencing to analyze …

Abstract RSAT (Regulatory Sequence Analysis Tools) is a suite of modular tools for the
detection and the analysis of cis-regulatory elements in genome sequences. Its main …

Cell fate decisions require appropriate regulation of key genes. Sox9, a direct target of SRY,
is pivotal in mammalian sex determination. In vivo high-throughput chromatin accessibility …

This article summarizes our progress with RegulonDB (http://regulondb. ccg. unam. mx/)
during the past 2 years. We have kept up-to-date the knowledge from the published …

Abstract RSAT (Regulatory Sequence Analysis Tools) is a modular software suite for the
analysis of cis-regulatory elements in genome sequences. Its main applications are (i) motif …

Abstract d-Glucosamine (GlcN) is a freely available and commonly used dietary supplement
potentially promoting cartilage health in humans, which also acts as an inhibitor of …