An excess of saturated fatty acids and simple sugars in the diet is a known environmental
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …

Obesity is now a worldwide health issue. Far from being limited to weight gain, obesity is
generally associated with low-grade inflammation and with a cluster of disorders collectively …

Hypertension is a highly prevalent condition with numerous health risks, and the incidence
of hypertension is greatest among older adults. Traditional discussions of hypertension have …

In the last decade, much attention has been devoted to the effects of nutrient-related signals
on brain development and cognitive functions. A turning point was the discovery that brain …

Vascular insults can initiate a cascade of molecular events leading to neurodegeneration,
cognitive impairment, and dementia. Here, we review the cellular and molecular …

The associations between consumption of a high-fat or 'Western'diet and metabolic
disorders such as obesity, diabetes, and cardiovascular disease have long been recognized …

Due to a sedentary lifestyle, more and more people are becoming obese nowadays. In
addition to health‐related problems, obesity can also impair cognition and motor …

Consumption of a Western Diet (WD) that is high in saturated fat and added sugars
negatively impacts cognitive function, particularly mnemonic processes that rely on the …

Metabolic syndrome (MetS), which is characterized by insulin resistance, high blood
glucose, obesity, and dyslipidemia, is known to increase the risk of dementia accompanied …

Evidence from human and animal studies suggests that high-energy diets impair cognitive
function. However, the conditions for such impairments are unclear as studies have differed …