Biofabricated tissues have found numerous applications in tissue engineering and
regenerative medicine in addition to the promotion of disease modeling and drug …

Context It is well recognized that some hypothyroid patients on levothyroxine (LT4) remain
symptomatic, but why patients are susceptible to this condition, why symptoms persist, and …

Clinical hypothyroidism affects one in 300 people in the United States, with a higher
prevalence among female and older patients. Symptoms range from minimal to life …

Importance Cardiovascular disease is the leading cause of death in the United States.
Synthetic thyroid hormones are among the 3 most commonly prescribed medications, yet …

Hypothyroidism is a common endocrinopathy, and levothyroxine is frequently prescribed.
Despite the basic tenets of initiating and adjusting levothyroxine being agreed on, there are …

Thyroid hormones (TH) have a significant impact on cellular oxidative metabolism. Besides
that, they maintain vascular homeostasis by positive effects on endothelial and vascular …

Thyroid hormones (TH) have a cardinal role in the development of the central nervous
system during embryogenesis and early infancy. However, the TH-responsive genes in the …

Hashimoto thyroiditis (HT) is a common autoimmune disorder, affecting women 7–10 times
more often than men, that develops because of genetic susceptibility, X chromosome …

Purpose To provide an overview of consequences of undertreatment with levothyroxine
(LT4) in the common non-communicable disease, hypothyroidism. Methods Narrative review …

Background: Between 10% and 15% of hypothyroid patients experience persistent
symptoms despite achieving biochemical euthyroidism. Unexplained persistent symptoms …