[HTML][HTML] Small nucleolar RNAs: insight into their function in cancer
J Liang, J Wen, Z Huang, X Chen, B Zhang… - Frontiers in …, 2019 - frontiersin.org
Small nucleolar RNAs (SnoRNAs) are a class of non-coding RNAs divided into two classes:
C/D box snoRNAs and H/ACA box snoRNAs. The canonical function of C/D box and H/ACA …
C/D box snoRNAs and H/ACA box snoRNAs. The canonical function of C/D box and H/ACA …
[HTML][HTML] tRNA-derived fragments: Mechanisms underlying their regulation of gene expression and potential applications as therapeutic targets in cancers and virus …
X Yu, Y Xie, S Zhang, X Song, B Xiao, Z Yan - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract tRNA-derived fragments (tRFs) are a new category of regulatory noncoding RNAs
with distinct biological functions in cancers and stress-induced diseases. Herein, we first …
with distinct biological functions in cancers and stress-induced diseases. Herein, we first …
[HTML][HTML] Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction
MJ Shurtleff, MM Temoche-Diaz, KV Karfilis, S Ri… - elife, 2016 - elifesciences.org
Exosomes are small vesicles that are secreted from metazoan cells and may convey
selected membrane proteins and small RNAs to target cells for the control of cell migration …
selected membrane proteins and small RNAs to target cells for the control of cell migration …
Broad role for YBX1 in defining the small noncoding RNA composition of exosomes
RNA is secreted from cells enclosed within extracellular vesicles (EVs). Defining the RNA
composition of EVs is challenging due to their coisolation with contaminants, lack of …
composition of EVs is challenging due to their coisolation with contaminants, lack of …
tRNA-derived fragments and tRNA halves: the new players in cancers
L Zhu, J Ge, T Li, Y Shen, J Guo - Cancer Letters, 2019 - Elsevier
Abstract tRNA-derived fragments (tRFs) and tRNA halves (tiRNAs) are small non-coding
RNAs derived from precursor tRNAs or mature tRNAs. Depending on the sources, tRFs can …
RNAs derived from precursor tRNAs or mature tRNAs. Depending on the sources, tRFs can …
[HTML][HTML] tRNA-derived fragments (tRFs): emerging new roles for an ancient RNA in the regulation of gene expression
SP Keam, G Hutvagner - Life, 2015 - mdpi.com
This review will summarise the recent discoveries and current state of research on short
noncoding RNAs derived from tRNAs—known as tRNA-derived fragments (tRFs). It will …
noncoding RNAs derived from tRNAs—known as tRNA-derived fragments (tRFs). It will …
[HTML][HTML] Cold shock proteins: from cellular mechanisms to pathophysiology and disease
JA Lindquist, PR Mertens - Cell Communication and Signaling, 2018 - Springer
Cold shock proteins are multifunctional RNA/DNA binding proteins, characterized by the
presence of one or more cold shock domains. In humans, the best characterized members of …
presence of one or more cold shock domains. In humans, the best characterized members of …
Identification of urinary exosomal noncoding RNAs as novel biomarkers in chronic kidney disease
R Khurana, G Ranches, S Schafferer, M Lukasser… - Rna, 2017 - rnajournal.cshlp.org
In chronic kidney disease (CKD), the decline in the glomerular filtration rate is associated
with increased morbidity and mortality and thus poses a major challenge for healthcare …
with increased morbidity and mortality and thus poses a major challenge for healthcare …
[HTML][HTML] Y-box binding proteins in mRNP assembly, translation, and stability control
D Mordovkina, DN Lyabin, EA Smolin, EM Sogorina… - Biomolecules, 2020 - mdpi.com
Y-box binding proteins (YB proteins) are DNA/RNA-binding proteins belonging to a large
family of proteins with the cold shock domain. Functionally, these proteins are known to be …
family of proteins with the cold shock domain. Functionally, these proteins are known to be …
[HTML][HTML] snoRNPs: functions in ribosome biogenesis
Ribosomes are perhaps the most critical macromolecular machine as they are tasked with
carrying out protein synthesis in cells. They are incredibly complex structures composed of …
carrying out protein synthesis in cells. They are incredibly complex structures composed of …