Treatment regimens with insulin analogues and haemoglobin A1c target of< 7% in type 2 diabetes: a systematic review

D Giugliano, MI Maiorino, G Bellastella… - Diabetes research and …, 2011 - Elsevier
We conducted a systematic review of randomized controlled trials that evaluated the
effectiveness of insulin regimens (basal, biphasic, prandial, and basal-bolus) with insulin …

Ten years of experience with biphasic insulin aspart 30: from drug development to the latest clinical findings

A Liebl, V Prusty, P Valensi, R Kawamori… - Drugs, 2012 - Springer
Abstract Biphasic insulin aspart 30 (BIAsp 30) includes 30% soluble rapid-acting insulin
aspart (IAsp) along with an intermediate-acting 70% protaminated IAsp that provides …

Comparison of insulin lispro mix 25 with insulin lispro mix 50 as insulin starter in Chinese patients with type 2 diabetes mellitus (CLASSIFY study): Subgroup analysis …

Q Su, C Liu, H Zheng, J Zhu, PF Li, L Qian… - Journal of …, 2017 - Wiley Online Library
背景目前推荐在中国糖尿病患者口服降糖药物治疗失败后, 以预混胰岛素作为起始胰岛素治疗.
本研究中, 我们在口服降糖药物治疗后血糖仍然控制不佳的中国2 型糖尿病患者中 …

Expert opinion: patient selection for premixed insulin formulations in diabetes care

S Kalra, L Czupryniak, G Kilov, R Lamptey, A Kumar… - Diabetes Therapy, 2018 - Springer
Premixed insulins are an important tool for glycemic control in persons with diabetes.
Equally important in diabetes care is the selection of the most appropriate insulin regimen …

Relationship of baseline HbA1c, HbA1c change and HbA1c target of< 7% with insulin analogues in type 2 diabetes: a meta‐analysis of randomised controlled trials

D Giugliano, M Maiorino, G Bellastella… - … Journal of Clinical …, 2011 - Wiley Online Library
Aim: We performed a meta‐analysis of randomised controlled trials (RCTs) with insulin
analogues in type 2 diabetes utilising a least‐squared regression model in order to assess …

Efficacy and safety of prandial premixed therapy using insulin lispro mix 50/50 3 times daily compared with progressive titration of insulin lispro mix 75/25 or biphasic …

E Farcasiu, T Ivanyi, B Mozejko-Pastewka, Z Birkus… - Clinical …, 2011 - Elsevier
BACKGROUND: Prandial premixed therapy 3 times daily has been proposed recently for
type 2 diabetes mellitus (T2DM) patients who fail to achieve glycemic control with commonly …

Multiple HbA1c targets and insulin analogues in type 2 diabetes: a systematic review

D Giugliano, MI Maiorino, G Bellastella… - Journal of Diabetes and …, 2011 - Elsevier
PROBLEM: Insulin analogues are increasingly used in patients with type 2 diabetes. We
performed a systematic review of randomized controlled trials (RCTs) to assess the role of …

Biphasic insulin aspart in the treatment of type 2 diabetes mellitus

D Cucinotta, GT Russo - Expert Opinion on Pharmacotherapy, 2009 - Taylor & Francis
Background: Initiating and implementing insulin treatment in type 2 diabetic subjects is a
major challenge in diabetes clinical practice. Although simple regimens, such as the …

药物性低血糖

李亚聪, 何继瑞 - 2014 - ir.lzu.edu.cn
摘要药物性低血糖是由于药物的使用导致血糖低于2.8 mmol/L 时所致的交感神经兴奋,
以及中枢神经损害的临床综合征. 患者一般先出现饥饿心慌, 大汗淋漓, 无力手抖 …

Mid‐and high‐ratio premix insulin analogues: potential treatment options for patients with type 2 diabetes in need of greater postprandial blood glucose control

JS Christiansen, A Liebl, JA Davidson… - Diabetes, Obesity …, 2010 - Wiley Online Library
Some patients with type 2 diabetes continue to have high postprandial blood glucose levels
on twice‐daily regimens of 'low‐ratio'premix insulin formulations (up to 30% rapid‐acting …