[HTML][HTML] Omicron variant (B. 1.1. 529) and its sublineages: What do we know so far amid the emergence of recombinant variants of SARS-CoV-2?

M Dhawan, ARA Saied, S Mitra, FA Alhumaydhi… - Biomedicine & …, 2022 - Elsevier
Since the start of the COVID-19 pandemic, numerous variants of SARS-CoV-2 have been
reported worldwide. The advent of variants of concern (VOCs) raises severe concerns amid …

Instructing durable humoral immunity for COVID-19 and other vaccinable diseases

D Bhattacharya - Immunity, 2022 - cell.com
Many aspects of SARS-CoV-2 have fully conformed with the principles established by
decades of viral immunology research, ultimately leading to the crowning achievement of …

Immune boosting by B. 1.1. 529 (Omicron) depends on previous SARS-CoV-2 exposure

CJ Reynolds, C Pade, JM Gibbons, AD Otter, KM Lin… - Science, 2022 - science.org
The Omicron, or Pango lineage B. 1.1. 529, variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) carries multiple spike mutations with high transmissibility and …

[HTML][HTML] Increased memory B cell potency and breadth after a SARS-CoV-2 mRNA boost

F Muecksch, Z Wang, A Cho, C Gaebler, T Ben Tanfous… - Nature, 2022 - nature.com
The Omicron variant of SARS-CoV-2 infected many vaccinated and convalescent
individuals,–. Despite the reduced protection from infection, individuals who received three …

Omicron spike function and neutralizing activity elicited by a comprehensive panel of vaccines

JE Bowen, A Addetia, HV Dang, C Stewart, JT Brown… - Science, 2022 - science.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of
concern comprises several sublineages, with BA. 2 and BA. 2.12. 1 having replaced the …

Recall of preexisting cross-reactive B cell memory after Omicron BA. 1 breakthrough infection

CI Kaku, AJ Bergeron, C Ahlm, J Normark… - Science …, 2022 - science.org
Understanding immune responses after severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) breakthrough infection will facilitate the development of next-generation …

Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection

MM Painter, TS Johnston, KA Lundgreen… - Nature …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of vaccinated
individuals is increasingly common but rarely results in severe disease, likely due to the …

[HTML][HTML] Inactivated vaccine-elicited potent antibodies can broadly neutralize SARS-CoV-2 circulating variants

Y Liu, Z Wang, X Zhuang, S Zhang, Z Chen… - Nature …, 2023 - nature.com
A full understanding of the inactivated COVID-19 vaccine-mediated antibody responses to
SARS-CoV-2 circulating variants will inform vaccine effectiveness and vaccination …

Memory B cell responses to Omicron subvariants after SARS-CoV-2 mRNA breakthrough infection in humans

Z Wang, P Zhou, F Muecksch, A Cho… - Journal of Experimental …, 2022 - rupress.org
Individuals who receive a third mRNA vaccine dose show enhanced protection against
severe COVID-19, but little is known about the impact of breakthrough infections on memory …

[HTML][HTML] Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose

L Renia, YS Goh, A Rouers, N Le Bert, WN Chia… - Nature …, 2022 - nature.com
Understanding the impact of age on vaccinations is essential for the design and delivery of
vaccines against SARS-CoV-2. Here, we present findings from a comprehensive analysis of …