Why venous leg ulcers have difficulty healing: overview on pathophysiology, clinical consequences, and treatment

JD Raffetto, D Ligi, R Maniscalco, RA Khalil… - Journal of clinical …, 2020 - mdpi.com
Venous leg ulcers (VLUs) are one of the most common ulcers of the lower extremity. VLU
affects many individuals worldwide, could pose a significant socioeconomic burden to the …

Microbiome and human aging: probiotic and prebiotic potentials in longevity, skin health and cellular senescence

JL Boyajian, M Ghebretatios, S Schaly, P Islam… - Nutrients, 2021 - mdpi.com
The role of the microbiome in human aging is important: the microbiome directly impacts
aging through the gastrointestinal system. However, the microbial impact on skin has yet to …

A stretchable wireless wearable bioelectronic system for multiplexed monitoring and combination treatment of infected chronic wounds

E Shirzaei Sani, C Xu, C Wang, Y Song, J Min, J Tu… - Science …, 2023 - science.org
Chronic nonhealing wounds are one of the major and rapidly growing clinical complications
all over the world. Current therapies frequently require emergent surgical interventions …

Nanotechnology-driven therapeutic interventions in wound healing: potential uses and applications

S Hamdan, I Pastar, S Drakulich, E Dikici… - ACS central …, 2017 - ACS Publications
The chronic nature and associated complications of nonhealing wounds have led to the
emergence of nanotechnology-based therapies that aim at facilitating the healing process …

Role of growth factors and cytokines in diabetic foot ulcer healing: a detailed review

M Zubair, J Ahmad - Reviews in Endocrine and Metabolic Disorders, 2019 - Springer
The aim of the review is to examine the role of growth factors and cytokines in the
management of Diabetic Foot Ulcers, such as platelet derived growth factor (PDGF) …

Update on chitosan-based hydrogels: Preparation, characterization, and its antimicrobial and antibiofilm applications

K Thirupathi, CJ Raorane, V Ramkumar, S Ulagesan… - Gels, 2022 - mdpi.com
Chitosan is a prominent biopolymer in research for of its physicochemical properties and
uses. Each year, the number of publications based on chitosan and its derivatives increases …

Wound healing strategies based on nanoparticles incorporated in hydrogel wound patches

P Dam, M Celik, M Ustun, S Saha, C Saha, EA Kacar… - RSC …, 2023 - pubs.rsc.org
The intricate, tightly controlled mechanism of wound healing that is a vital physiological
mechanism is essential to maintaining the skin's natural barrier function. Numerous studies …

Smart battery-free and wireless bioelectronic platform based on a nature-skin-derived organohydrogel for chronic wound diagnosis, assessment, and accelerated …

Z Bai, X Wang, M Huang, Y Feng, S Sun, M Zheng… - Nano Energy, 2023 - Elsevier
Using smart electroactive hydrogels with emerging bioelectronics to monitor wound status
wirelessly in real-time is a promising approach as an unremitting therapy for refractory …

Wound healing applications of creams and “smart” hydrogels

D Stan, C Tanase, M Avram, R Apetrei… - Experimental …, 2021 - Wiley Online Library
Although superficial wounds are often easy to treat for healthy individuals, there are some
more severe types of wounds (burns, ulcers, diabetic wounds, etc.) that are a challenge for …

[HTML][HTML] Recent advances in biosensors for real time monitoring of pH, temperature, and oxygen in chronic wounds

K Youssef, A Ullah, P Rezai, A Hasan, A Amirfazli - Materials Today Bio, 2023 - Elsevier
Chronic wounds are among the major healthcare issues affecting millions of people
worldwide with high rates of morbidity, losses of limbs and mortality. Microbial infection in …